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| | In the areas of biology and biophysics, Dr. Gratton utilizes his knowledge of the latest techniques in fluorescence spectroscopy and microscopy to image live cells. As head of the Laboratory for Fluorescence Dynamics, a National Center for Research Resources supported by the National Institutes of Health, he and the scientists in his lab use fluorescence to study cellular processes including protein aggregation, membrane interactions, and migration of cells, to track moving particles, and to analyze collagen formation and deformation. The research leads to a better understanding of cell function, with potential application to diagnosing and identifying treatment for many human diseases, including Huntington's disease, kidney disorders, and cancers. Their findings also lead to the development of new fluorescence instrumentation and to the continued advancement of his center's data analysis software, Globals for Spectroscopy and Globals for Imaging. Proceeds from the software are used to fund research-related conferences and workshops, reflecting the longstanding commitment of Dr. Gratton and his lab to disseminating the latest advances in biomedical research to the greater scientific community. | | In the areas of biology and biophysics, Dr. Gratton utilizes his knowledge of the latest techniques in fluorescence spectroscopy and microscopy to image live cells. As head of the Laboratory for Fluorescence Dynamics, a National Center for Research Resources supported by the National Institutes of Health, he and the scientists in his lab use fluorescence to study cellular processes including protein aggregation, membrane interactions, and migration of cells, to track moving particles, and to analyze collagen formation and deformation. The research leads to a better understanding of cell function, with potential application to diagnosing and identifying treatment for many human diseases, including Huntington's disease, kidney disorders, and cancers. Their findings also lead to the development of new fluorescence instrumentation and to the continued advancement of his center's data analysis software, Globals for Spectroscopy and Globals for Imaging. Proceeds from the software are used to fund research-related conferences and workshops, reflecting the longstanding commitment of Dr. Gratton and his lab to disseminating the latest advances in biomedical research to the greater scientific community. |
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| − | B-1Gratton, E. and R. Lopez-Delgado. Remarks on a novel method for fluorescence lifetime measurements. In Time Resolved Fluorescence Spectroscopy in Biochemistry and Biology (R. B. Cundall and R. E. Dale, Eds.) NATO ASIS, Ser. A. Vol. 69A, Plenum Press, NY, pp. 109-114 (1983).
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| − | B-2Jameson, D. and E. Gratton. Analysis of heterogeneous emissions by multifrequency phase and modulation fluorometry. In New Directions in Molecular Luminescence. ASTM-STP 822 (D. Eastwood, Ed.) (American Society of Testing and Materials), pp. 67-81 (1983).
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| − | B-3Careri, G. and E. Gratton. The statistical time correlation approach to enzyme action: The role of hydration. In The Fluctuating Enzyme, Ch. X, pp. 227-262 (G. R. Welch, Ed.) Wiley & Sons, NY (1984).
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| − | B-4Gratton, E., J. R. Alcala and G. Marriott. Rotational motions of tryptophan and tyrosine residues in proteins. In Structure and Dynamics of Nucleic Acids, Proteins, and Membranes (E. Clementi and S. Chin, Eds.) 149-151 (1986).
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| − | B-5Gratton, E., N. Silva and S. Ferreira. Fluorescence of tryptophan and protein dynamics. In Biological and Artificial Intelligence Systems (E. Clementi and S. Chin, Eds.) 49-55 (1988).
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| − | B-6Lentz, B. R., S. W. Burgess and E. Gratton. Concentration dependence of DPHpPC fluorescence lifetime: Photophysics and utility for monitoring membrane fusion. In Molecular Mechanisms of Membrane Fusion (S. Ohki, D. Doyle, T. D. Flanagan, S. W. Hue and E. Mayhew, Eds.) Plenum Pub. Corp. (1988).
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| − | B-7Gratton, E., J. R. Alcala and F. G. Prendergast. Protein dynamics: Fluorescence lifetime distributions. In Fluorescent Biomolecules, pp. 17-32 (D. M. Jameson and G. Reinhart, Eds.) Plenum Press (1989).
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| − | B-8Gratton, E. and M. J. vandeVen. Laser sources for confocal microscopy. In The Handbook of Biological Confocal Microscopy (J. Pawley, Ed.) Ch. 5, pp. 53-67. Plenum Press, Proc. EMSA 47th Annual Mtg., San Antonio, TX (1990).
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| − | B-9Gratton, E., J. R. Alcala and B. Barbieri. Frequency domain fluorometry. In Handbook of Luminescence Techniques in Chemical and Biochemical Analysis (W.R.G. Baeyens, D. De Keukeleire and K. Korkidis. Eds.) Marcel Dekker, Inc., pp. 47-72 (1991).
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| − | B-10 Beechem, J. M., E. Gratton, M. Ameloot, J. R. Knutson and L. Brand. The global analysis of fluorescence intensity and anisotropy decay data: Second generation theory and programs. In Topics in Fluorescence Spectroscopy, II "Principles." (J. R. Lakowicz, Ed.) Ch. 5, pp. 241-305 (1991).
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| − | B-11 Parasassi, T., M. Di Stefano, G. Ravagnan, O. Sapora and E. Gratton. Membrane aging during cell growth ascertained by Laurdan generalized polarization. In Experimental Cell Research 202, Academic Press, 432-439 (1992).
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| − | B-12 Ferreira, S. T. and E. Gratton. Enzyme activity in reverse micelles: Roles of diffusion and extent of hydration. In Biomolecules in Organic Solvents, CRC Meeting, Ch. 8, pp. 189-201 (1992).
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| − | B-13 Reinhart, G., E. Gratton and W. Mantulin. Dissociation of large oligomeric proteins by high hydrostatic pressure: dynamic light scattering studies. NATO ASI Series Volume "High Pressure Chemistry, Biochemistry and Materials Sciences." (R. Winter, Ed.), 619-626 (1993).
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| − | B-14 vandeVen, M. and E. Gratton. Time-resolved fluorescence lifetime imaging. In Optical Microscopy: Emerging Methods and Applications, Academic Press, Ch. 14, 373-402 (1993).
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| − | B-15 Gratton, E. and M. J. vandeVen. Laser sources for confocal microscopy. In The Handbook of Biological Confocal Microscopy, Second Edition (J. Pawley, Ed.) Plenum Press Ch. 5 pp. 69-97 (1995).
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| − | B-16 So, P. T. C., T. French, W. M. Yu, K. M. Berland, C. Y. Dong, and E. Gratton. Two photon microscopy: Time-resolved and intensity imaging. In Fluorescence Imaging Spectroscopy and Microscopy (Wang, X. F. and B. Herman, Eds.) Chemical Analysis Series, Vol. 137, John Wiley & Sons, Inc., Ch. 11, 351-374 (1996).
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| − | B-17 French, T., P. T. C. So, C. Y. Dong, K. M. Berland and E. Gratton. Fluorescence lifetime imaging techniques for microscopy. In "Methods in Cell Biology." Video Microscopy. Greenfield Sluder and David Wolf, Eds., Vol. 56, pp. 227-304 (1997).
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| − | B-18 Fantini, S., B. Barbieri, M. A. Franceschini and E. Gratton. Frequency-domain spectroscopy. In Applications of Optical Engineering to the Study of Cellular Pathology, E. Kohen, ed., (Research Signpost, Trivandum, India), pp. 57-66 (1997). [abstract]
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| − | B-19 So, P. T. C., C. Y. Dong, K. M. Berland, T. French and E. Gratton. Time-resolved stimulated-emission and transient-absorption microscopy and spectroscopy. In Topics in Fluorescence Spectroscopy, Vol. 5: Nonlinear and Two-Photon-Induced Fluorescence, Chapter 10. Plenum Press, NY. Ed., J. R. Lakowicz, pp. 427-469 (1997).
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| − | B-20 Fantini, S., S. A. Walker, M. A. Franceschini, K. T. Moesta, P. M. Schlag, M. Kaschke, and E. Gratton. Optical characterization of breast tumors by frequency-domain optical mammography, OSA Trends in Optics and Photonics Series 21, Eds., James G. Fujimoto and Michael S. Patterson, 143147 (1998).
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| − | B-21 Franceschini, M. A., A. Paunescu, S. Fantini, S. Pratesi, J. S. Maier, G. P. Donzelli, and G. Gratton, Frequency-domain optical measurements in vitro on two- and three-layered tissue-like phantoms, and in vivo on infant heads, OSA Trends in Optics and Photonics Series 21, Eds., James G. Fujimoto and Michael S. Patterson, 232-236 (1998).
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| − | B-22 Paunescu, A., M. A. Franceschini, S. Fantini, A. Cerussi, and E. Gratton, Effective optical properties of two-layered turbid media using the frequency-domain multi-distance method, OSA Trends in Optics and Photonics Series 21, Eds., James G. Fujimoto and Michael S. Patterson, 79-83 (1998).
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| − | B-23 Toronov, V., M. Filiaci, S. Fantini, and E. Gratton, Study of large scale fluctuations in turbid media by photon-density-wave fluctuation correlation spectroscopy, OSA Trends in Optics and Photonics Series 21, Eds., James G. Fujimoto and Michael S. Patterson, 60-62 (1998).
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| − | B-24 So, P. T. C., B. R. Master, E. Gratton, and I. E. Kochevar, Two-photon optical biopsy of thick tissues, OSA Trends in Optics and Photonics Series 22, Eds., Eva M. Sevick-Muraca, Joseph A. Izatt, and Marwood N. Ediger, 40-42 (1998).
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| − | B-25 Filiaci, M., V. Toronov, S. Fantini, and E. Gratton, Optical probe and frequency-domain instrumentation to study spatial and temporal correlations of fluctuations in tissues, OSA Trends in Optics and Photonics Series 22, Eds., Eva M. Sevick-Muraca and Joseph A. Izatt, 183-187 (1998).
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| − | B-26 Masters, B. R., P. T. C. So, W. W. Mantulin, and E. Gratton, Tissue Microscopy and Spectroscopy: A Two-Photon Approach, OSA Trends in Optics and Photonics Series 22, Eds., Eva Sevick-Muraca, Joseph A. Izatt, and Marwood N. Ediger, 43-45 (1998).
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| − | B-27 Cerussi, A., S. Fantini, and E. Gratton, Quantitative fluorescence spectroscopy in strongly scattering media containing multiple fluorophores, OSA Trends in Optics and Photonics Series 22, Eds., Eva M. Sevick-Muraca, Joseph A. Izan, and Marwood N. Ediger, pp. 70-75 (1998).
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| − | B-28 Chen, Y., J. D. Müller, K. M. Berland, and E. Gratton. Fluorescence Fluctuation Spectroscopy, In Confocal Microscopy: Methods in Enzymology 19(2) eds. P. Michael Conn, (Academic Press), pp. 234-252 (1999).
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| − | B-29 Masters, B. R., P. T. C. So., K. H. Kim., C. Buehler, and E. Gratton. Multiphoton excitation microscopy, confocal microscopy, and spectroscopy of living cells and tissues; functional metabolic imaging of human skin in vivo. Confocal Microscopy (methods in Enzymology, Vol. 307). By JN Abelson, MI Simon, and PM Conn (Editors). Academic Press, pp. 513-36, 1999. ISBN: 01521822087
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| − | B-30 Gratton, E. Laser sources for confocal and two-photon microscopy. In Confocal and Two-Photon Microscopy: Foundations, Applications and Advances. A. Diaspro, ed., Wiley & Sons, Inc. (2000).
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| − | B-31 Yu, W., W. W. Mantulin, and E. Gratton. Fluorescence Lifetime Imaging: New Microscopy Technologies. In: Emerging Tools for Single-Cell Analysis, G. Durack and J. P.Robinson, eds. (Wiley-Liss, Inc.), pp. 139-173 (2000).
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| − | B-32 Müller, J. D., Y. Chen, and E. Gratton. Photon counting histogram statistics. In: Fluorescence Correlation Spectroscopy. Theory and Applications, E. L. Elson and R. Rigler, eds. (Springer Publishers) Ch. 20, pp. 410-435 (2001).
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| − | B-33 Muller, J., Y. Chen, and E. Gratton. Fluorescence Correlation Spectroscopy. In: Methods in Enzymology 361, Ch. 4, pp. 69-92, G. Marriott and I. Parker, eds. (2003).
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| − | B-34 Dong CY, T. French, P. T. So, C. Buehler, K. M. Berland and E. Gratton. Fluorescence-lifetime imaging techniques for microscopy. In: Methods Cell Biol., 2nd Edition, G. Sluder and D. E. Wolf, eds., Vol. 72, pp. 431-64(2003).
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| − | B-35 Bagatolli, L. A., S. Sanchez, T. Hazlett and E. Gratton. Giant vesicles, Laurdan, and two-photon fluorescence microscopy: evidence of lipid lateral separation in bilayers. In: Methods of Enzymology 360, Ch. 20, pp 481-500, G. Marriott, ed. (2003).
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| − | B-36 Gratton, E. and S. Fantini. Reflectance and Transmittance Spectroscopy. In Laser and Current Optical Techniques in Biology, Vol. 4, Ch. 11, R. Pratesi and G. Palumbo, eds. pp. 211-258 (2004).
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| − | B-37 Gratton, E., S. Breusegem, N. Barry, Q. Ruan, and J. Eid. Fluctuation correlation spectroscopy in cells: Determination of molecular aggregation. Chapter 1 in: Biophotonics-Optical Science and Engineering for the 21st Century, Kluwer Academic/Plenum Publishers. Shen, X. Van Wijk, R.;(Eds.) XVIII, pp. 1-14. ISBN: 0-387-24995-8 (2005).
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| − | B-38 S A Sánchez, M A Tricerri, G Gunther, and E Gratton. Laurdan generalized polarization: from cuvette to microscope. In Modern Research and Educational Topics in Microscopy. Vol. 2: Applications in Physical/Chemical Sciences (Microscopy Book Series, Vol. 3). By A Méndez-Vilas and J Díaz (Editors). Formatex Research Center, Badajoz, Spain, pp. 1007-1014 (2007). ISBN: 9788461194209
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| − | B-39 A Celli, C Y Lee, and E Gratton. Fluorescence microscopy to study pressure between lipids in giant unilamellar vesicles. In Methods in Membrane Lipids (Methods in Molecular Biology, Vol. 400). By AM Dopico (Editors). Humana Press, pp. 333-340 (2007). ISBN: 1588296628
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| − | B-40 M A Digman and E Gratton. The RICS method: measurement of fast dynamics in cells with the laser scanning microscope. In Image Analysis in Medical Microscopy and Pathology. By HS Wu and AJ Einstein (Editors). Research Signpost, Kerala, pp. 207-224 (2007). ISBN: 8130801167
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| − | B-41 V Levi and E Gratton. Three-Dimensional particle tracking in a laser scanning fluorescence microscope. In Single-particle tracking and single molecule energy transfer. By C Bräuchle, DC Lamb, and J Michaelis (Editors). Wiley VCH, pp. 3-24, 2010. ISBN: 9783527322961
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| − | B-42 E Gratton, V Toronov, U Wolf and M Wolf. Detection of Brain Activity by Near-Infrared Light. In Biomedical Optical Imaging. By JG Fujimoto and D Farkas (Editors). Oxford University Press, pp. 378-395, 2009. ISBN: 9780195150445
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| − | B-43 Learmonth, R. P. and E. Gratton. Assessment of membrane fluidity in individual yeast cells by Laurden Generalized Polarization and multi-photon scanning fluorescence microscopy. In: Fluorescence Spectroscopy, Imaging and Probes. By R Kraauenof, AJWG Visser, and HC gerritsen (Editors). Springer-Verlag berlin, Heidelberg, New York, pp. 241-252, 2002. ISBN: 9783540427681
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| − | B-44 Dong, C. Y., C. Buehler, P. T. C. So., T. French, and E Gratton. Biological applications of time-resolved, pump-probe fluorescence microscopy and spectroscopy in the frequency domain. In: Methods in Cellular Imaging (Methods in Physiology Series, Vol. IV). By A Periasamy (Editors). American Physiology Society, pp. 324-344, 2001. ISBN: 9780195139365
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| − | B-45 Dong, C. Y., K. H. Kim, C. Buehler, L. Hsu, H. Kim, P. T. C. So., B. R. Masters, E. Gratton, and I. E. Kochevar. Probing deep-tissue structures by two-photon fluorescence microscopy. In: Emerging tools for Single-Cell Anaylsis (Advances in Optical Measurement Technologies). By G. Durack and JP Robinson (Editors). Wiley-Liss, Inc. pp. 221-237, 2000. ISBN: 9780471315759
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| − | Journal Articles:
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| − | J-1 Gratton, E. The Acid Denaturation of DNA. Rap. 1st. Sup. San. 155, 46 pp. (1971).
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| − | J-2 Grandolfo, M., E. Gratton, F. Anfosso Somma and P. Vecchia. Exciton binding energies of layer-type semiconductors GaSe and GaTe. Phys. Stat. Sol.(b) 48, 729-735 (1971).
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| − | J-3 Gratton, E. Method for the automatic correction of scattering in absorption spectra by using the integrating sphere. Biopolymers 10, 2629-2634 (1971).
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| − | J-4 Dore, E., C. Frontali and E. Gratton. The role of ions in the acid melting of DNA. Biopolymers 11, 2033-2041 (1972).
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| − | J-5 Dore, E., C. Frontali and E. Gratton. Physico-chemical description of a condensed form of DNA. Biopolymers 11, 443-459 (1972).
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| − | J-6 Cancellieri, A., C. Frontali and E. Gratton. Dispersion effect on turbidimetric size measurements. Biopolymers 13, 735-743 (1974).
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| − | J-7 Gentile, S. and E. Gratton. Misure di Costante Dielettrica su polveri di lisozima idratato. Rap. Ist. Fis. Roma 561 (1974).
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| − | J-8 Careri, G., P. Fasella and E. Gratton. Statistical time events in enzymes: A physical assessment. Crit. Rev. Biochem. 3, 141-164 (1975).
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| − | J-9 G. Careri, A. Giansanti and E. Gratton, Eds. Studio I.R. dell'idratazione del lisozima. Rap. Ist. Fis. Roma (1977).
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| − | J-10 Giannini, L. and E. Gratton. Hydration of globular proteins: U.V. studies. Rend. Acc. Naz. Lincei. Sci. Fis. Mat. Natl. 62, 711-715 (1977).
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| − | J-11 Careri, G., L. De Angelis, E. Gratton and C. Messana. Magnetic susceptibility of lysozyme. Phys. Lett. 60A, 490-491 (1977).
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| − | J-12 Careri, G. and E. Gratton. Onsager coupling in enzymes. Biosystems 8, 185-186 (1977).
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| − | J-13 Ascoli, F., E. Gratton, F. Riva, P. Fasella and M. Brunori. Infrared stretching frequencies of CO in carbomonoxyhemoglobin from trout. Biochim. Biophys. Acta 553, 534-537 (1978).
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| − | J-14 Gratton, E. and R. Lopez-Delgado. The harmonic content of a SR pulse: The possibility to reach subpicosecond resolution in the fluorescence decay experiment. SSRL Report No. 78/09 (1978).
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| − | J-15 Gratton, E. and R. Lopez-Delgado. Use of synchrotron radiation for the measurement of fluorescence lifetimes with subpicosecond resolution. Rev. Sci. Inst. 50, 789-790 (1979).
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| − | J-16 Careri, G., P. Fasella and E. Gratton. Enzyme dynamics: The statistical physics approach. Ann. Rev. Biophys. and Bioeng. 8, 69-97 (1979).
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| − | J-17 Careri, G., A. Giansanti and E. Gratton. Lysozyme film hydration events--An IR and gravimetric study. Biopolymers 18, 1187- 1203 (1979).
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| − | J-18 Frontali, C., E. Dore, A. Ferrauto, E. Gratton, A. Bettini, M. R. Pozzan and E. Valdevit. An absolute method for the determination of the persistence length of native DNA from electron micrographs. Biopolymers 18, 1353-1373 (1979).
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| − | J-19 Gratton, E. Hydration induced mobility in azurin. Proc. of the III Intl. Conf. "De la Physique Theorique a la Biologie" Springer, Vienna, July (1979).
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| − | J-20 Gratton, E. The time dimension of protein systems. Adv. Physiol. Sci. 3, 269-273 (1980).
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| − | J-21 Gratton, E. and R. Lopez-Delgado. Measuring fluorescence decay times by phase-shift and modulation techniques using the high harmonic content of pulsed light sources. I1 Nuovo Cimento 56B, 110-124 (1980).
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| − | J-22 Careri, G., E. Gratton, P.-H. Yang and J. A. Rupley. Correlation of IR spectroscopic, heat capacity, diamagnetic susceptibility and enzymatic measurements on lysozyme powder. Nature 284, 572-573 (1980).
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| − | J-23 Careri, G., A. Giansanti and E. Gratton. Molecular aspects of the hydration process in a globular protein. Int. J. Quantum Chem. Vol. XIX, pp. 1133-1135 (1981).
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| − | J-24 Gratton, E. and M. Limkeman. A continuously variable frequency cross-correlation phase fluorometer with picosecond resolution. Biophys. J. 44, 315-324 (1983).
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| − | J-25 Careri, G., U. Buontempo, F. Carta, E. Gratton and A. Scott. Infrared absorption in acetanilide by solitons. Phys. Rev. Lett. 51(4), 304-307 (1983).
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| − | J-26 Gavish, B., E. Gratton, C. J. Hardy and A. St. Denis. Differential sound velocity apparatus for the investigation of protein solutions. Rev. Sci. Inst. 54, 1756-1760 (1983).
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| − | J-27 Gratton, E. and M. Limkeman. Microprocessor-controlled photon-counting spectrofluorometer. Rev. Sci. Inst. 54(3), 294-299 (1983).
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| − | J-28 Gratton, E., N. Rosato, D. M. Jameson, F. Antonangeli, F. Bassani, F. Campolungo, U. Grassano, A. Finazzi-Agró, M. Piacentini A. Savoia, G. Weber and N. Zema. A multifrequency phase-fluorometer with picosecond resolution using synchrotron
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| − | radiation. INFN-PULS Frascati Report, 65 pp. (1983).
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| − | J-29 Rupley, J. A., E. Gratton and G. Careri. Water and globular proteins. Trends in Biochem. 8, 18-22 (1983).
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| − | J-30 Gavish, B., E. Gratton and C. J. Hardy. Adiabatic compressibility of globular proteins. Proc. Natl. Acad. Sci. USA 80, pp. 750-754 (1983).
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| − | J-31 Lakowicz, J. R., E. Gratton, H. Cherek and B. P. Maliwal. Frequency-domain phase-modulation fluorometry: Resolution of complex decays of fluorescence intensity and anisotropy. J. of Lumin. 31&32, 699-702 (1984).
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| − | J-32 Parasassi, T., F. Conti, M. Glaser and E. Gratton. Detection of phospholipids phase separation. A multifrequency phase fluorimetry study of 1,6-diphenyl-1,3,5-hexatriene fluorescence. J. Biol. Chem. 259(22), 14011-14017 (1984).
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| − | J-33 Lakowicz, J. R., H. Cherek, G. Laczko and E. Gratton. Time-resolved fluorescence emission spectra of labeled phospholipid vesicles, as observed using multifrequency phase fluorometry. Biochim. Biophys. Acta 777, 183-193 (1984).
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| − | J-34 Lakowicz, J. R., E. Gratton, H. Cherek, B. P. Maliwal and G. Laczko. Determination of time-resolved fluorescence emission spectra and anisotropies of a fluorophore-protein complex using frequency- domain phase-modulation fluorometry.
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| − | J. Biol. Chem. 259(17), 10967- 10972 (1984).
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| − | J-35 Careri, G., U. Buontempo, F. Galluzzi, A. C. Scott, E. Gratton and E. Shyamsunder. Spectroscopic evidence for Davydov-like solitons in acetanilide. Phys. Rev. B 30 (8), 4689-4702 (1984).
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| − | J-36 Parasassi, T., F. Conti and E. Gratton. Study of heterogeneous emission of parinaric acid isomers using multifrequency phase fluorometry. Biochemistry 23(23), 5660-5664 (1984).
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| − | J-37 Conti, F., T. Parasassi, N. Rosato, O. Sapora and E. Gratton. Fluorescence studies using synchrotron radiation on normal and differentiated cells labeled with parinaric acids. Biochim. Biophys. Acta 805, 117-122 (1984).
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| − | J-38 Gratton, E., M. Limkeman, J. R. Lakowicz, B. P. Maliwal, H. Cherek and G. Laczko. Resolution of mixtures of fluorophores using variable-frequency phase and modulation data. Biophys. J. 46, 479486 (1984).
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| − | J-39 Lakowicz, J. R., G. Laczko, H. Cherek, E. Gratton and M. Limkeman. Analysis of fluorescence decay kinetics from variable-frequency phase shift and modulation data. Biophys. J. 46, 463-477 (1984).
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| − | J-40 Marque, J., L. Eisenstein, E. Gratton, J. M. Sturtevant and C. J. Hardy. Thermodynamic properties of purple membrane. Biophys. J. 46, 567-572 (1984).
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| − | J-41 Gratton, E., D. M. Jameson and R. Hall. Multifrequency phase and modulation fluorometry. Ann. Rev. Biophys. Bioeng. 13, 105- 124 (1984).
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| − | J-42 Jameson, D. M., E. Gratton and R. Hall. The measurement and analysis of heterogeneous emissions by multifrequency phase and modulation fluorometry. App. Spec. Rev. 20, 55-106 (1984).
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| − | J-43 Jameson, D., E. Gratton, G. Weber and B. Alpert. Oxygen distribution and migration within mbdes fe and hbdes fe: multifrequency phase and modulation fluorometry study. Biophys. J. 45, 795- 803 (1984).
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| − | J-44 Gratton, E., D. M. Jameson, N. Rosato and G. Weber. Multifrequency cross-correlation phase fluorometer using synchrotron radiation. Rev. Sci. Inst. 55, 486-494 (1984).
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| − | J-45 Gratton, E., D. Jameson, G. Weber and B. Alpert. A model of dynamic quenching of fluorescence in globular proteins. Biophys. J. 45, 789-794 (1984).
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| − | J-46 Alcala, R., E. Gratton and D. M. Jameson. A multifrequency phase fluorometer using the harmonic content of a mode-locked laser. Anal. Inst. 14(3&4), 225-250 (1985).
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| − | J-47 Lakowicz, J. R., B. P. Maliwal and E. Gratton. Recent developments in frequency-domain fluorometry. Anal. Inst. 14(3&4), 193-223 (1985).
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| − | J-48 Mugnier, J., B. Valeur and E. Gratton. Rate of intramolecular energy transfer in coumarin bichromophoric molecules. An investigation by multifrequency phase-modulation fluorometry. Chem. Phys. Lett. 119 (2&3) 217-222 (1985).
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| − | J-49 Scott, A. C., E. Gratton, E. Shyamsunder and G. Careri. IR overtone spectrum of the vibrational soliton in crystalline acetanilide. Phys. Rev. Lett. B 32, 5551-5553 (1985).
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| − | J-50 Frauenfelder, H. and E. Gratton. Protein dynamics and hydration. In Methods in Enzymology 127, "Biomembranes, Protons and Water: Structure and Translocation." (1985).
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| − | J-51 Gratton, E. and D. M. Jameson. New approach to phase and modulation resolved spectra. Anal. Chem. 57, 1694-1697 (1985).
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| − | J-52 Lakowicz, J. R., H. Cherek, B. Maliwal and E. Gratton. Time- resolved fluorescence anisotropies of diphenylhexatriene and perylene in solvents and lipid bilayers obtained by multifrequency phase-modulation fluorometry.
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| − | Biochemistry 24, 376-383 (1985).
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| − | J-53 Gratton, E. and J. R. Lakowicz. Ultrafast dynamics in proteins and membranes by time resolved fluorescence spectroscopy. In Structure and Motion: Membranes, Nucleic Acids, and Proteins (E. Clementi, G. Corongiu, M. H. Sarma and
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| − | A. R. Sarma, Eds.) Adenine Press, NY, pp. 155-168 (1985).
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| − | J-54 Gratton, E. and B. Barbieri. Multifrequency phase fluorometry using pulsed sources: Theory and applications. Spectroscopy 1 (6), 28-36 (1986).
| |
| − | J-55 Gratton, E., J. R. Alcala, G. Marriott and F. G. Prendergast. Fluorescence studies of protein dynamics. In Proc. International Symposium of Computer Analysis for Life Sciences. Progress and Challenges in Biological and Synthetic Polymer
| |
| − | Research, HAYASHIBARA FORUM '85 (C. Kawabata and A. R. Bishop, Eds.) Tokyo, Japan, pp. 1-11 (1986).
| |
| − | J-56 Parasassi, T., F. Conti and E. Gratton. Time-resolved fluorescence emission spectra of Laurdan in phospholipid vesicles by multifrequency phase and modulation fluorometry. Cell. and Mol. Biol. 32, 103-108 (1986).
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| − | J-57 Parasassi, T., F. Conti and E. Gratton. Fluorophores in a polar medium: time dependence of emission spectra detected by multifrequency phase and modulation fluorometry. Cell. and Mol. Biol. 32(1), 99-102 (1986).
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| − | J-58 Rosato, N., A. Finazzi-Agró, E. Gratton, S. Stefanini and E. Chiancone. Time-resolved fluorescence of Apoferritin and its subunits. J. Biol. Chem. 262, 14487-14491 (1987).
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| − | J-59 Glaser, M., E. Gratton, T. Parasassi, O. Sapora and F. Conti. Spectroscopic investigation of the physical state of biological membranes using the fluorescence methodology. In Proc., 2nd Conf. on The State of Art of Research in the Chemistry
| |
| − | Department, La Sapienze, Rome, pp. 293-301 (1987).
| |
| − | J-60 Lentz, B. R., S. W. Burgess and E. Gratton. Concentration dependence of DPHpPC fluorescence lifetime: Photophysics and utility for monitoring membrane fusion. In Proc. of International Symp. on Mole. Mech. of Membrane Fusion, Buffalo,
| |
| − | NY (1987).
| |
| − | J-61 Eccleston, J., E. Gratton and D. M. Jameson. Interactions of a fluorescence analog of GDP with elongation factor Tu: steady-state and time resolved fluorescence studies. Biochemistry 26, 39023907 (1987).
| |
| − | J-62 Jameson, D. M., E. Gratton and J. Eccleston. Intrinsic fluorescence of elongation factor Tu in its complexes with GDP and elongation factor Tu. Biochemistry 26, 3894-3901 (1987).
| |
| − | J-63 Fiorini, R., M. Valentino, S. Wang, M. Glaser and E. Gratton. Fluorescence lifetime distributions of 1,6-diphenyl-1-3-5-hexatriene in phospholipid vesicles. Biochemistry 26, 3864-3870 (1987).
| |
| − | J-64 Alcala, R., E. Gratton and F. G. Prendergast. Interpretation of fluorescence decays in proteins using continuous lifetime distributions. Biophys. J. 51, 925-936 (1987).
| |
| − | J-65 Bismuto, E., G. Irace, G. Colonna, D. M. Jameson and E. Gratton. Dynamic aspects of the heme binding site in phylogenetically distant myoglobins. Biochim. Biophys. Acta 913, 150-154 (1987).
| |
| − | J-66 Schroeder, F., Y. Barenholz, E. Gratton and T. E. Thompson. A fluorescence study of dehydroergosterol in phosphatidylcholine bilayers vesicles. Biochemistry 26, 2441-2448 (1987).
| |
| − | J-67 Gratton, E. and B. Barbieri. Molecular dynamics studies using frequency-domain fluorometry. SPIE Proc., Vol. 743, 104-109 (1987).
| |
| − | J-68 Parasassi, T., F. Conti, E. Gratton and 0. Sapora. Membranes modifications of differentiating proerythroblast. Variation of 1,6-diphenyl-1,3,5-hexatriene lifetime distributions by multifrequency phase and modulation fluorometry.
| |
| − | Biochim. Biophys. Acta 898(2), 196-201 (1987).
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| − | J-69 Gratton, E., J. R. Alcala and G. Marriott. Rotations of tryptophan residues in proteins. Biochem. Soc. Trans., 617th Meeting, Dundee 14, 835-838 (1987).
| |
| − | J-70 Bismuto, E., D. M. Jameson and E. Gratton. Dipolar relaxations in glycerol: a dynamic fluorescence study of 4-2'-(dimethylamino)-6'-naphthoylcyclohexanecarboxylic acid (DANCA). J. Am. Chem. Soc. 109, 2354-2357 (1987).
| |
| − | J-71 Alcala, J. R., E. Gratton and F. G. Prendergast. Fluorescence lifetime distributions in proteins. Biophys. J. 51, 597-604 (1987).
| |
| − | J-72 Barbieri, B., E. Gratton, W. W. Mantulin, J. J. Sparrow. Continuous lifetime distributions and rotations of tryptophan residues in proteins. Thirty-eight Pittsburgh Conf. & Expo. on Analytical Chem. and Appl. Spec., Atlantic City, NJ, March 8-13,
| |
| − | No. 996 (1987).
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| − | J-73 Alcala, R., E. Gratton and F. G. Prendergast. Resolvability of fluorescence lifetime distributions using phase fluorometry. Biophys. J. 51, 587-596 (1987).
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| − | J-74 Barbieri, B., F. DePicoli and E. Gratton. Resolution of overlapping spectra using frequency-domain fluorometry. In Proc. SPIE 909, Time-Resolved Laser Spectroscopy in Biochemistry. J. R. Lakowicz, ed., 366-369 (1988).
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| − | J-75 Beechem, J. M. and E. Gratton. Fluorescence spectroscopy data analysis environment: A second generation Global analysis program. In Proc. SPIE 909, Time-Resolved Laser Spectroscopy in Biochemistry. J. R. Lakowicz, ed., 70-81 (1988).
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| − | J-76 Schroeder, F., G. Nemecz, Y. Barenholz, E. Gratton and T. E. Thompson. Cholestatrienol time resolved fluorescence in phosphatidylcholine bilayers. In Proc. SPIE 909, Time-Resolved Laser Spectroscopy in Biochemistry. J. R. Lakowicz, ed.,
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| − | 457-465 (1988).
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| − | J-77 Bismuto, E., E. Gratton and G. Irace. Effect of unfolding on the tryptophanyl fluorescence lifetime distribution in apomyoglobin. Biochemistry 27, 2132-2136 (1988).
| |
| − | J-78 Careri, G., E. Gratton and E. Shyamsunder. Fine structure of the amide I band in acetanilide. Phys. Rev. A, 37(10), 4048-4051 (1988).
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| − | J-79 Fiorini, R. M., M. Valentino, M. Glaser, E. Gratton and E. Curatola. Fluorescence lifetime distributions of 1,6-diphenyl-1,3,5-hexatriene reveal the effect of cholesterol on the microheterogeneity of erythrocyte membrane. Biochim. Biophys.
| |
| − | Acta 939 , 485-492 (1988).
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| − | J-80 Valentino, M., M. Governa, E. Gratton, R. Fiorini, G. Curatola, E. Bertoli. Increased membrane heterogeneity in stimulated human granulocytes. FEBS Letters 234(2), 451-454 (1988).
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| − | J-81 Schroeder, F., G. Nemecz, E. Gratton, Y. Barenholz and T. E. Thompson. Fluorescence properties of cholestatrienol in phosphatidylcholine bilayer vesicles. Biophys. Chem. 32, 57-72 (1988).
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| − | J-82 Thompson, R. B. and E. Gratton. Phase fluorometric method for determination of standard lifetimes. Anal. Chem. 60, 670- 674 (1988).
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| − | J-83 Fiorini, R., E. Gratton and G. Curatola. Effect of cholesterol on membrane microheterogeneity: A study using 1,6-diphenyl-1,3,5- hexatriene fluorescence lifetime distributions. Biochim. Biophys. Acta 006 (2), 198-202 (1989).
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| − | J-84 Wratten, M. L., E. Gratton, M. vandeVen and A. Sevanian. DPH lifetime distributions in vesicles containing phospholipid hydroperoxidides. BBRC 164 , 169-175 (1989).
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| − | J-85 Barcellona, M. L. and E. Gratton. Fluorescence lifetime distributions of DNA/4'6-diamidino-2phenylindole complex. Biochim. Biophys. Acta. 993, 174-178 (1989).
| |
| − | J-86 Barbieri, B. F. DePicoli and E. Gratton. Synthesizers' phase noise in frequency-domain fluorometry. Rev. Sci. Inst. 60, 3201- 3206 (1989).
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| − | J-87 Piston, D. W. and E. Gratton. Orientational exchange approach to fluorescence anisotropy decay. Biophys. J. 56., 1083-1091 (1989).
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| − | J-88 Gratton, E. and M. vandeVen. A superheterodyning microwave phase fluorometer with femtosecond resolution using a microchannel plate. Rev. Sci. Inst. LFD Report 18 (1989).
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| − | J-89 Rosato, N., E. Gratton, G. Mei, I. Savini and A. Finazzi-Agrò. Dynamic fluorescence in copper proteins: Selected examples. Proc. Satellite FEBS 1989 Symp. Biochem. and Biophys. Approaches to the Study of Copper Proteins, Camerino, Italy
| |
| − | (1989).
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| − | J-90 Cardiel, G., M. L. Barcellona and E. Gratton. Polydeoxynucleotides/DAPI interactions: A fluorescence study by multifrequency phase fluorometry. The Italian J. of Biochem. 38, 125-129 (1989).
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| − | J-91 Parasassi, T. and E. Gratton. Detection of phospholipid bilayers microheterogeneity and domains by fluorescence spectroscopy. Proc. Serono Symposium on Membrane Technology in Clinical Pathology Biochemistry and Pharmacology. Raven
| |
| − | Press, 109-117 (1989).
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| − | J-92 Govindjee, M. vandeVen, C. Preston, M. Seibert and E. Gratton. Recombinational light emission from photosystem II reaction centers. 8th Int'l Conf. on Photosynthesis, Stockholm, Sweden (1989).
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| − | J-93 Feddersen, B. M., D. W. Piston and E. Gratton. Digital parallel acquisition in frequency domain fluorimetry. Rev. Sci. Inst. 60(9), 2929-2936 (1989).
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| − | J-94 Piston, D. W., G. Marriott, T. Radivoyevich, R. M. Clegg, T. M. Jovin and E. Gratton. Wide-band acousto-optic light modulator for frequency domain fluorometry and phosphorimetry. Rev. Sci. Inst. 60(8), 2596- 2600 (1989).
| |
| − | J-95 Bismuto, E., G. Irace and E. Gratton. Multiple conformational states in myoglobin revealed by frequency domain fluorometry. Biochemistry 28, 1508-1512 (1989).
| |
| − | J-96 Piston, D. W., T. Bilash and E. Gratton. Compartmental analysis approach to fluorescence anisotropy: Perylene in viscous solvents. J. Phys. Chem. 93, 3963-3967 (1989).
| |
| − | J-97 Gratton, E., W. W. Mantulin, M. J. vandeVen, J. B. Fishkin, M. B. Maris and B. Chance. The possibility of a near-infrared optical imaging system using frequency domain methods. Proc. Third Int'l Conf. for Peace through Mind/Brain Science, pp.
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| − | 183-189, Hamamatsu City, Japan (1990).
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| − | J-98 Rosato, N., E. Gratton, G. Mei and A. Finazzi-Agrò. Fluorescence lifetime distributions in human superoxide dismutase: Effect of temperature and denaturation. Biophys. J. 58, 817-822 (1990).
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| − | J-99 Pin, S., C. A. Royer, E. Gratton, B. Alpert and G. Weber. Subunit interactions in hemoglobin probed by fluorescence and high-pressure techniques. Biochemistry 29, 9194-9202 (1990).
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| − | J-100 Barcellona, M. L., G. Cardiel and E. Gratton. Time-resolved fluorescence of DAPI in solution and bound to polydeoxynucleotides. Biochem. Biophys. Res. Commun. 170(1), 270-280 (1990).
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| − | J-101 Gratton, E., B. Feddersen and M. vandeVen. Parallel acquisition of fluorescence decay using array detectors. In: Proc. SPIE 1204, Time-Resolved Laser Spectroscopy in Biochemistry II. J. R. Lakowicz, ed. 21-25 (1990).
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| − | J-102 Barbieri, B. F., F. de Piccoli, M. Vandeven, and E. Gratton. What determines the uncertainty of phase and modulation measurements in frequency-domain fluorometry? In: Proc. SPIE 1204, Time-Resolved Laser Spectroscopy in Biochemistry II. J.
| |
| − | R. Lakowicz, ed. 158-170 (1990).
| |
| − | J-103 Vander Meulen, D. L., D. G. Nealon, E. Gratton and D. M. Jameson. Excitation wave-length dependent fluorescence anisotropy of Eosin- Myosin adducts: Evidence for anisotropic rotations. Biophys. Chem. 36, 177-184 (1990).
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| − | J-104 Parasassi, T., G. De Stasio, A. d'Ubaldo and E. Gratton. Phase fluctuation in phospholipid membranes revealed by Laurdan fluorescence. Biophys. J. 57, 1179-1186 (1990).
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| − | J-105 Rosato, N., G. Mei, E. Gratton, J. V. Bannister, W. H. Bannister and A. Finazzi-Agrò. A time-resolved fluorescence study of human copper-zinc superoxide dismutase. Biophys. Chem. 36, 41-46 (1990).
| |
| − | J-106 Parasassi, T., G. De Stasio, A. Miccheli, F. Bruno, F. Conti and E. Gratton. Abscisic acid induced microheterogeneity in phospholipid vesicles. A fluorescence study. Biophys. Chem. 35, 65-73 (1990).
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| − | J-107 Barcellona, M. L. and E. Gratton. The fluorescence properties of a DNA probe: 4'-6-diamidino-2phenylindole (DAPI). E. Biophys. J. 17, 315-323 (1990).
| |
| − | J-108 Govindjee, M. vandeVen, C. Preston, M. Seibert and E. Gratton. Chlorophyll a fluorescence lifetime distribution functions in open and closed photosystem II reaction center preparations; analysis by multifrequency phase fluorometry. Biochim.
| |
| − | Biophys. Acta 173-179 (1990).
| |
| − | J-109 Ferreira, S. and E. Gratton. Hydration and protein substates: fluorescence of proteins in reverse micelles, J. Mol. Liq. Special Issue in Honor of G. Careri, 253-272 (1990).
| |
| − | J-110 Parasassi, T., G. De Stasio, G. Ravagnan, R. M. Rusch and E. Gratton. Quantitation of lipid phases in phospholipid vesicles by the generalized polarization of Laurdan fluorescence. Biophysical J., 60, 179-189 (1991).
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| − | J-111 Reinhart, G., P. Marzola, D. M. Jameson and E. Gratton. A method for on-line background subtraction in frequency domain fluorometry. J. of Fluorescence 1(3) 153-162 (1991).
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| − | J-112 Di Iorio, E. E., U. R. Hiltpold, D. Filipovic, K. H. Winterhalter, E. Gratton, E. Vitrano, A. Cupane, M. Leone and L. Cordone. Protein dynamics: comparative investigation on heme-proteins with different physiological roles. Biophys. J., 59, 742-754
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| − | (1991).
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| − | J-113 Chance, B., J. S. Leigh and E. Gratton. New Image. Nature, 349 (6311), 660 (1991).
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| − | J-114 Fishkin, J., E. Gratton, M. J. vandeVen and W. W. Mantulin. Diffusion of intensity modulated near-infrared light in turbid media. In Proc. SPIE 1431, Time- Resolved Spectroscopy and Imaging of Tissues. B. Chance and A. Katzer, eds., 122-135
| |
| − | (1991).
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| − | J-115 Fishkin, J. B., B. A. Feddersen and E. Gratton. Experimental study of the diffraction of photon density waves by an absorbing edge in highly scattering media. Proc. IEEE MTT-S International Microwave Symp., Boston, MA. (1991).
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| − | J-116 Marzola, P. and E. Gratton. Hydration and protein dynamics: Frequency domain fluorescence spectroscopy on proteins in reverse micelles. J. Phys. Chem. 95, 9488-9495 (1991).
| |
| − | J-117 Barcellona, M. L. and E. Gratton. A molecular approach to 4'-6-diamidine-2-phenylindole (DAPI) photophysical behavior at different pH values. Biophys. Chem. 40, 223-229 (1991).
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| − | J-118 Wang, S., J. M. Beechem, E. Gratton and M. Glaser. Orientational distribution of 1,6-diphenyl-1,3,5hexatriene in phospholipid vesicles as determined by Global analysis of frequency domain fluorimetry data. Biochemistry 30 (22), 5565-5572
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| − | (1991).
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| − | J-119 Parasassi, T., G. De Stasio, R. M. Rusch and E. Gratton. A photophysical model for 1,6-Diphenyl1,3,5-Hexatriene fluorescence decay in solvents and in phospholipid vesicles. Biophys. J. 59(2), 466475 (1991).
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| − | J-120 Axelsen, P. H., E. Gratton and F. G. Prendergast. Experimentally verifying molecular dynamics simulations through fluorescence anisotropy measurements. Biochemistry 30, 1173-1179 (1991).
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| − | J-121 Parasassi, T. and E. Gratton. Packing of phospholipid vesicles studied by oxygen quenching of Laurdan fluorescence. J. Fluorescence, 2 (3), 167-174 (1992).
| |
| − | J-122 Parasassi, T., G. Ravagnan, O. Sapora and E. Gratton. Membrane oxidative damage induced by ionizing radiation detected by diphenylhexatriene fluorescence lifetime distributions. Int. J. Rad. Biol. 61(6), 791-796 (1992).
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| − | J-123 Mei, G., N. Rosato, N. Silva, R. Rusch, E. Gratton, I. Savini and A. Finazzi-Agrò. Denaturation of human Cu/Zn superoxide dismutase by guanidine hydrochloride: A dynamic fluorescence study. Biochem. J. 31(32), 7224-7230 (1992).
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| − | J-124 Gratton, E. Frequency domain fluorescence lifetime measurements using synchrotron radiation. In Synchrotron Radiation and Dynamic Phenomena (A. Beswick, Ed.) Conf. Proc. 258, Particles and Fields Series 49, 453-464 (1992).
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| − | J-125 Gratton, E., N. Silva, G. Mei, N. Rosato, I. Savini and A. Finazzi-Agró. Fluorescence lifetime distribution of folded and unfolded proteins. Int'l J. of Quantum Chem. 2, 1479-1489 (1992).
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| − | J-126 Bucci, E., Z. Gryczynski, E. Gratton and T. Tenenholz. Heme- tryptophan relationships in hemoglobin explored by frequency-domain time- resolved fluorescence at 10 GHz resolution. In Proc. SPIE 1640, Time-Resolved Laser Spectroscopy in
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| − | Biochemistry III. J. R. Lakowicz, ed., 784791 (1992).
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| − | J-127 Clegg, R. M., B. Feddersen, E. Gratton and T. M. Jovin. Time resolved imaging fluorescence microscopy. In Proc. SPIE 1640, Time-Resolved Laser Spectroscopy in Biochemistry III. J. R. Lakowicz, ed., 448-460 (1992).
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| − | J-128 Berland, K., E. Gratton and M. vandeVen. A laser heterodyning detector for frequency-domain ultrafast spectroscopy. In Proc. SPIE 1640, Time-Resolved Laser Spectroscopy in Biochemistry III. J. R. Lakowicz, ed., 370-378 (1992).
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| − | J-129 Van Der Meer, B. W., M. A. Raymer, S. L. Wagoner, R. L. Hackney, J. M. Beechem, & E. Gratton. Models for fluorescence energy transfer between moving donors and acceptors. In Proc. SPIE 1640, Time-Resolved Laser Spectroscopy in
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| − | Biochemistry III. J. R. Lakowicz, ed., 220-229 (1992).
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| − | J-130 French, T., E. Gratton and J. Maier. Frequency domain imaging of thick tissues using a CCD. In Proc. SPIE 1640, Time-Resolved Laser Spectroscopy in Biochemistry III. J. R. Lakowicz, ed., 254261 (1992).
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| − | J-131 vandeVen, M., B. Barbieri, E. Gratton and J. Maier. Analysis of noise sources in frequency domain fluorometry. In Proc. SPIE 1640, Time-Resolved Laser Spectroscopy in Biochemistry III. J. R. Lakowicz, ed., 332-341 (1992).
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| − | J-132 Fishkin, J. and E. Gratton. Diffraction of intensity modulated light in strongly scattering media in the presence of a "semi-infinite" absorbing or reflecting plane bounded by a straight edge. In Proc. SPIE 1640, Time-Resolved Laser Spectroscopy in
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| − | Biochemistry III. J. R. Lakowicz, ed., 362-367 (1992).
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| − | J-133 Silva, N., E. Gratton, G. Mei, N. Rosato, R. Rusch and A. Finazzi-Agrò. Molten globule monomers in human superoxide dismutase. Biophys. Chem. 48, 171-182 (1993).
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| − | J-134 Bismuto, E., E. Gratton, I. Sirangelo, and G. Irace. Structure and dynamics of the acidic compact state of apomyoglobin by frequency-domain fluorometry. Eur. J. Biochem. 218, 213-219, (1993).
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| − | J-135 Mantulin, W. W., J. B. Fishkin, P. T. C. So, E. Gratton and J. S. Maier. Quantitative diffusive wave spectroscopy in tissues. In Proc. SPIE 1888, Photon Migration and Imagining in Random Media and Tissues. B. Chance and R. R. Alfano, eds.,
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| − | 420-427 (1993).
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| − | J-136 Maier, J. S. and E. Gratton. Frequency-domain methods in optical tomography: detection of localized absorbers and a backscattering reconstruction scheme. Photon Migration and Imagining in Random Media and Tissues (B. Chance and R. R.
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| − | Alfano, Ed.), SPIE Proc. 1888, 440-451 (1993).
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| − | J-137 Govindjee, M. vandeVen, J. Cao, C. Royer and E. Gratton. Multifrequency cross-correlation phase fluorometry of chlorophyll a fluorescence in thylakoid and PSII-enriched membranes. Photochem. and Photobiol. 58 (3), 438-445 (1993).
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| − | J-138 Mantulin, W. W., T. French and E. Gratton. Optical imaging in the frequency domain. In: Proc. SPIE 1892, Medical Laser and Systems II. D. M. Harris and C. KM. Penny, eds., 158-166 (1993).
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| − | J-139 Zolese, G., R. Staffolani, L. Mazzanti and E. Gratton. Effect of divalent cations on Na+, K+ -ATPase obtained from human placenta. Fed. of European Biochem. Soc. 323 (1,2) 11-14 (1993).
| |
| − | J-140 Van Der Meer, B. W., M. A. Raymer, S. L. Wagoner, R. L. Hackney, J. M. Beechem, and E. Gratton. Designing matrix models for fluorescence energy transfer between moving donors and acceptors. Biophys. J. 64(4), 1243-1263 (1993).
| |
| − | J-141 Fiorini, R., G. Curatola, A. Kantar, P. L. Giorgi and E. Gratton. Use of Laurdan fluorescence in studying plasma membrane organization of polymorphonuclear leukocytes during the respiratory burst. Photochem. and Photobiol. 57 (3), 438-441
| |
| − | (1993).
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| − | J-142 Levi, M., P. V. Wilson, O. J. Cooper and E. Gratton. Lipid phases in renal brush border membranes revealed by Laurdan fluorescence. Photochem. and Photobiol. 57(3), 420-425 (1993).
| |
| − | J-143 Parasassi, T., G. Ravagnan, R. M. Rusch and E. Gratton. Modulation and dynamics of phase properties in phospholipid mixtures detected by Laurdan fluorescence. Photochem. and Photobiol. 57(3), 403-410 (1993).
| |
| − | J-144 Gratton, E., W. W. Mantulin, M. J. vandeVen, J. B. Fishkin, M. B. Maris and B. Chance. A novel approach to laser tomography. Bioimaging 40-46 (1993).
| |
| − | J-145 Fishkin, J. and E. Gratton. Propagation of photon density waves in strongly scattering media containing an absorbing "semi-infinite" plane bounded by a straight edge. J. of the Optical Soc. of America A. 10(1), 127-140 (1993).
| |
| − | J-146 Maris, M., E. Gratton, J. Maier, W. Mantulin and B. Chance. Functional near-infrared imaging of deoxygenated hemoglobin during exercise of the finger extensor muscles using the frequency-domain technique. Bioimaging 2, 174-183 (1994).
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| − | J-147 Berland, K. M., So, P. T. C. and E. Gratton. Two-photon fluorescence correlation spectroscopy: method and application to the intracellular environment. Biophys. J. 68, 694-701 (1995).
| |
| − | J-148 Silva, N., E. Gratton and G. Mei. Proteins fluorescence and conformational substates: The dynamics of human superoxide dismutase. Comments on Cell. and Mol. Biophys. 8 (4), 217-242 (1994).
| |
| − | J-149 Maier, J. S., S. A. Walker, S. Fantini, M. A. Franceschini and E. Gratton. Possible correlation between blood glucose concentration and reduced scattering coefficient of tissues in the near-infrared. Optics Letters 19 (24), 2062-2064 (1994).
| |
| − | J-150 Parasassi, T., M. Di Stefano, M. Loiero, G. Ravagnan and E. Gratton. Cholesterol modifies water concentration and dynamics in phospholipid bilayers. A fluorescence study using Laurdan probe. Biophys. J. 66, 763-766 (1994).
| |
| − | J-151 Parasassi, T., M. Di Stefano, M. Loiero, G. Ravagnan and E. Gratton. Influence of cholesterol on phospholipid bilayers phase domains as detected by Laurdan fluorescence. Biophys. J. 66, 120-132 (1994).
| |
| − | J-152 Parasassi, T., A. M. Giusti, E. Gratton, E. Monaco, M. Raimondi, G. Ravagnan and O. Sapporo. Evidence for an increase in water concentration in bilayers after oxidative damage of phospholipids induced by ionizing radiation. Int. J. Radiat. Biol.
| |
| − | 65, 329-334 (1994).
| |
| − | J-153 Ferreira, S. T. and E. Gratton. Anisotropic rotational diffusion of the adenine moiety in 1,N6ethenoadenosine triphosphate (-ATP) in viscous solvents investigated by time-resolved fluorescence spectroscopy. J. of the Amer. Chem. Soc. 116 (13),
| |
| − | 5791-5795 (1994).
| |
| − | J-154 Fantini, S., M. A. Franceschini, J. B. Fishkin, B. Barbieri and E. Gratton. Quantitative determination of the absorption spectra of chromophores in strongly scattering media: a light-emitting-diode based technique. Appl. Opt. 33 (22), 5204-5213
| |
| − | (1994).
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| − | J-155 Gratton, E., S. Fantini, M. A. Franceschini, J. B. Fishkin and J. Maier. Near-infrared optical spectroscopy of tissues using an LED frequency domain spectrometer. Proc. Advances in Optical Imaging & Photon Migration Topical Mtg. 21 (R. R.
| |
| − | Alfano, Ed., Proc. Optical Soc. of Amer.) 278282 (1994).
| |
| − | J-156 So, P., T. French and E. Gratton. A frequency domain time-resolved microscope using a fast-scan CCD camera. In Proc. SPIE 2137, Time resolved Laser Spectroscopy in Biochemistry IV, J. R. Lakowicz, ed., 83-92 (1994).
| |
| − | J-157 Gryczynski, Z. C.Fronticelli, E. Gratton, J. Lubkowski, E. Bucci. Effect of disordered hemes and dimerization in isolated a-subunits of hemoglobin detected by time-resolved fluorescence spectroscopy in the picosecond range. In Proc. SPIE 2137,
| |
| − | Time resolved Laser Spectroscopy in Biochemistry IV, J. R. Lakowicz, ed., 129-134 (1994).
| |
| − | J-158 Fantini, S., M. A. Franceschini and E. Gratton. Semi-infinite geometry boundary problem for light migration in highly scattering media: a frequency-domain study in the diffusion approximation. J. Optical Soc. of Amer.11(10), 2128-2138 (1994).
| |
| − | J-159 Fantini, S., M. A. Franceschini, J. B. Fishkin and E. Gratton. Absolute measurement of absorption and scattering coefficients spectra of a multiply scattering medium. In: Proc. SPIE 2131, Biomedical Fiber Optic Instrumentation, A. Katzir, ed., 356-
| |
| − | 364 (1994).
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| − | J-160 Fantini, S., M. A. Franceschini and E. Gratton. LED based quantitative measurement of absorption and scattering coefficient spectra of a strongly scattering medium. In Proc. SPIE 2131, Biomedical Fiber Optic Instrumentation. A. Katzir, ed., 356-
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| − | 364 (1994).
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| − | J-161 Franceschini, M. A., S. Fantini and E. Gratton. LED's in frequency-domain spectroscopy of tissues. In Proc SPIE 2135, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases. R. R. Alfano, ed., 300-306 (1994).
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| − | J-162 Mantulin, W. W. and E. Gratton. Spectroscopic innovations at the Laboratory for Fluorescence Dynamics. In: Proc. SPIE 2100, Cell and Biotissue Optics: Applications in Laser Diagnostics and Therapy. V. V. Tuchin, ed., 6-18 (1994).
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| − | J-163 Fantini, S., M. A. Franceschini, J. B. Fishkin, W. W. Mantulin and E. Gratton. The absorption spectra of a chromophore in highly scattering media. In: Proc. SPIE 2100, Cell and Biotissue Optics: Applications in Laser Diagnostics and Therapy. V.
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| − | V. Tuchin, ed., 114-123 (1994).
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| − | J-164 Brunet, J. E., V. Vargas, E. Gratton and D. Jameson. Hydrodynamics of horseradish peroxidase revealed by global analysis of multiple fluorescence probes. Biophys. J. 66, 446-453 (1994).
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| − | J-165 Ferreira, S. T., L. Stella and E. Gratton. Conformational dynamics of bovine Cu, Zu superoxide dismutase revealed by time-resolved fluorescence spectroscopy of the single tyrosine residue. Biophys. J. 66, (4), 1185-1196 (1994).
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| − | J-166 Gratton, G., J. S. Maier, M. Fabiani, W. W. Mantulin and E. Gratton. Feasibility of intracranial near-infrared optical scanning. Psychophysiology 31, 211-215 (1994).
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| − | J-167 Gratton, E. and J. Maier. Frequency-domain measurements of photon migration in highly scattering media. In Proc. SPIE Medical Optical Tomography: Functional Imaging and Monitoring. G. Müller, B. Chance, R. Alfano, S. Arridge, J. Beuthan,
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| − | E. Gratton, M. Kaschke, B. Masters, S. Svanberg and P. van der Zee, eds., 534-544 (1994).
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| − | J-168 Parasassi, T., M. Loiero, M. Raimondi, G. Ravagnan and E. Gratton. Absence of lipid gel-phase domains in seven mammalian cell lines and in four primary cell types. Biochim. Biophys. Acta 1153, 143-154 (1994).
| |
| − | Bernsdorff, C., R. Winter, T. L. Hazlett, and E. Gratton. Influence of Cholesterol and BSitosterol on the Dynamic Behaviour of DPPC as Detected by TMA-DPH and PyrPc Fluorescence: A Fluorescence Lifetime Distribution and Time-Resolved Anisotropy Study, Ber. Bunsenges. Phys. Chem. 99, 1479-1488 (1995).
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| − | J-169 So, P. T. C., T. French, W. M. Yu, K. M. Berland, C. Y. Dong, and E. Gratton. Time-resolved fluorescence microscopy using two photon excitation. Bioimaging 3, 49-63 (1995).
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| − | J-170 Giusti, A. M., E. Gratton, T. Parasassi, M. Raimondi and G. Ravagnan. Cholesterol effects on membrane structure and dynamics as detected by Laurdan fluorescence. Biochimica in Italia 3 64-72 (1995).
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| − | J-171 Parasassi, T., A. M. Giusti, M. Raimondi, G. Ravagnan, O. Sapora and E. Gratton. Cholesterol protects the phospholipid bilayer from oxidative damage. Free Radical Biol. and Med. 19 (4), 511516 (1995).
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| − | J-172 Gratton, G., M. Fabiani, D. Friedman, M. A. Franceschini, S. Fantini, P. M. Corballis, and E. Gratton. Rapid changes of optical parameters in the human brain during a tapping task. J. Cognitive Neuroscience 7 (4), 446-456 (1995).
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| − | J-173 Gratton, E. and J. B. Fishkin. Optical spectroscopy of tissue-like phantoms using photon density waves. Comments on Cell. and Mol. Biophys. 8(6), 309-359 (1995).
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| − | J-174 Franceschini, M. A., S. Fantini, S. A. Walker, J. S. Maier, W. W. Mantulin and E. Gratton. Multichannel optical instrument for near-infrared imaging of tissue. In Proc. SPIE 2389, Optical Tomography, Photon Migration, and Spectroscopy of Tissue
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| − | and Model Media: Theory, Human Studies, and Instrumentation. B. Chance, R. R. Alfano, eds., 264-273 (1995).
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| − | J-175 J. S. Maier, B. Barbieri, A. Chervu, I. Chervu, S. Fantini, M. A. Franceschini, M. Levi W. W. Mantulin, A. Rosenberg, S. A. Walker and E. Gratton. In vivo study of human tissues with a portable near-infrareD tissue spectrometer. In Proc. SPIE
| |
| − | 2387, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases II, R.R. Alfano, ed., 240-248 (1995).
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| − | J-176 Ferrari, M., R. A. De Blasi, S. Fantini, M. A. Franceschini, B. Barbieri, V. Quaresima and E. Gratton. Cerebral and muscle oxygen saturation measurement by a frequency-domain near-infrared spectroscopic technique. In Proc. SPIE 2389,
| |
| − | Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases II, R.R. Alfano, ed., 868-874 (1995).
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| − | J-177 Fantini, S., M. A. Franceschini, S. A. Walker, J. S. Maier and E. Gratton. Photon path distributions in turbid media: applications for imaging. In Proc. SPIE 2389, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases II,
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| − | R.R. Alfano, ed., 340-349 (1995).
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| − | J-178 Walker, S. A., A. E. Cerussi and E. Gratton. Back-projection image reconstruction using photon density waves in tissues. In Proc. SPIE 2389, Advances in Laser and Light Spectroscopy to Diagnose Cancer and Other Diseases II, R.R. Alfano, ed.,
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| − | 350-357 (1995).
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| − | J-179 Gratton, E. and T. Parasassi. Fluorescence lifetime distributions in membrane systems. J. of Fluorescence 5 (1), 51-57 (1995).
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| − | J-180 Parasassi, T., A. M. Giusti, M. Raimondi and E. Gratton. Abrupt modification of phospholipid bilayer properties at critical cholesterol concentrations, Biophys. J. 68 (5), 1895-1902 (1995).
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| − | J-181 Maier, J. S., S. Fantini, M. A. Franceschini-Fantini, W. W. Mantulin, S. A. Walker and E. Gratton. Application of a portable near-infrared spectrometer in the study of several human tissues. SPIE Proc. 2387 240-248 (1995).
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| − | J-182 Mantulin, W. W., S. Fantini, M. A. Franceschini-Fantini, S. A. Walker, J. S. Maier, and E. Gratton. Tissue optical parameter map generated with frequency domain spectroscopy. In: SPIE Proc., 2396, Biomedical Optoelectronic Instrumentation. A.
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| − | Katzir, J. A. Harrington, D. M. Harris, eds., 323-330 (1995).
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| − | J-183 Fantini, S., M. A. Franceschini, J. S. Maier, S. A. Walker and E. Gratton. Frequency-domain multisource optical spectrometer and oximeter, In: Proc. SPIE 2326 Photon Transport in Highly Scattering Tissue; Biomedical Optics Europe'94, Lille,
| |
| − | France. S. Avrillier, B. Chance, G. J. Mueller, A. V. P., V. V. Tuchin, eds., 108-115 (1995).
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| − | J-184 Carrero, J., D. M. Jameson and E. Gratton. Oxygen penetration and diffusion into myoglobin revealed by quenching of Zincprotoporphyrin IX fluorescence. Biophys. Chem. 54 143-154 (1995).
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| − | J-185 Fishkin, J. B., P. T. C. So, A. E. Cerussi, S. Fantini, M. A. Franceschini and E. Gratton. Frequency-domain method for determining spectral properties in multiple scattering media: methemoglobin absorption spectrum in a tissue-like phantom.
| |
| − | Applied Optics 34 (7), 1143-1155 (1995).
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| − | J-186 Fantini, S., M. A. Franceschini, J. S. Maier, S. A. Walker, B. Barbieri and E. Gratton. Frequency-domain multichannel optical detector for non-invasive tissue spectroscopy and oximetry. Opt. Eng. 34 (1), 32-42 (1995).
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| − | J-187 De Blasi, R. A., S. Fantini, M. A. Franceschini, M. Ferrari and E. Gratton. Cerebral and muscle oxygen saturation measurement by a novel frequency-domain near-infrared spectrometer. Medical & Biological Engineering & Computing 33, 228-230
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| − | (1995).
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| − | J-188 Parasassi, T. and E. Gratton. Membrane lipid domains and dynamics as detected by Laurdan fluorescence. J. of Fluorescence. 5 (1), 59-69 (1995).
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| − | J-189 Dong, C. Y., P. T. C. So, T. French, and E. Gratton. Fluorescence lifetime imaging by asynchronous pump-probe microscopy. Biophys. J. 69, 2234-2242 (1995).
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| − | J-190 Gratton, E., C. Y. Dong, P. T. C. So. Fluorescence Lifetime Microscopy: A Stimulated-emission Approach. In: Proc. SPIE 2678, Optical Diagnostics of Living Cells and Biofluids. D. L. Farkas, R. C. Leif, A. V. Priezzhev, T. Asakura, B. J.
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| − | Tromberg, eds., 98-109 (1996).
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| − | J-191 Walker, S., S. Fantini and E. Gratton. Back-projection reconstructions of cylindrical inhomogeneities from frequency domain optical measurements in turbid media. OSA Trends in Optics and Photonics on Advances in Optical Imaging and Photon
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| − | Migration 2, R. R. Alfano and J. G. Fujimoto, eds., 137141 (1996).
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| − | J-192 Maier, J. S., A. Cerussi, S. Fantini, M. A. Franceschini and E. Gratton. Quantitative fluorescence in tissue-like media. OSA Trends in Optics and Photonics on Biomedical Optical Spectroscopy and Diagnostics 3, E. Sevick-Muraca and D. Benaron,
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| − | eds., 206-209 (1996).
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| − | J-193 Cerussi, A., J. Maier, S. Fantini, M. A. Franceschini and E. Gratton. The frequency-domain multi-distance method in the presence of curved boundaries. OSA Trends in Optics and Photonics on Biomedical Optical Spectroscopy and Diagnostics 3,
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| − | E. Sevick-Muraca and D. Benaron, eds., 92-97 (1996).
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| − | J-194 Franceschini, M. A., S. Fantini, A. Cerussi, B. Barbieri, B. Chance and E. Gratton. The effect of water in the quantitation of hemoglobin concentration in a tissue-like phantom by near-infrared spectroscopy. OSA Trends in Optics and Photonics 3,
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| − | E. Sevick-Muraca and D. Benaron, eds., 126130 (1996).
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| − | J-195 Mei, G., A. Di Venere, G. Gilardi, N. Rosato, R. McKay, E. Gratton and A. Finazzi-Agró. Two classes of tryptophans in ascorbate oxidase revealed by time resolved fluorescence. OSA Trends in Optics and Photonics on Advances in Optical
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| − | Imaging and Photon Migration 2, R. R. Alfano and J. G. Fujimoto, Eds. (1996).
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| − | J-196 Bismuto, E., G. Irace, E. Sirangelo and E. Gratton. Pressure-induced perturbation of ANSapomyoglobin complex: Frequency domain fluorescence studies on native and acidic compact states. Protein Science 5(1) 121-126 (1996).
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| − | J-197 Berland, K. M., P. T. C. So, Y. Chen, W. W. Mantulin and E. Gratton. Scanning two-photon fluctuation correlation spectroscopy: Particle counting measurements for detection of molecular aggregation. Biophys. J. 71, 410-420 (1996).
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| − | J-198 Gratton, E., S. Fantini, M. A. Franceschini, S. Walker, and J. Maier. Spectroscopy and tomography of tissues in the frequency-domain. October 14-18, 1995, Proc. NATO ARW Workshop on Analytical Use of Fluorescent Probes in Oncology,
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| − | Miami FL (1996).
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| − | J-199 Parasassi, T. and E. Gratton. Comments on DPH fluorescence decrease at critical cholesterol concentration in phospholipid membranes. Biophys. J. March (1996).
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| − | J-200 Barcellona, M. L. and E. Gratton. Torsional dynamics and orientation of DNA-DAPI complexes. Biochemistry 35, 321-333 (1996).
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| − | J-201 Barcellona M. L. and E. Gratton. Fluorescence anisotropy of DNA/DAPI complex: Torsional dynamics and geometry of the complex. Biophys. J. 70 (5), 2341-2351 (1996).
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| − | J-202 Yu, W., P. T. C. So, T. French, and E. Gratton. Fluorescence generalized polarization of cell membranes-a two photon scanning microscopy approach. Biophys. J. 70, 626-636 (1996).
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| − | J-203 Gratton, E., G. Gratton, M. Fabiani and P. M. Corballis. Detection of brain activity using time-resolved interfered techniques. Proc. 5th Conference on Mind-Brain Science Hamamatsu City, Japan. (1996).
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| − | J-204 Fishkin, J. B., S. Fantini, M. J. van de Ven, and E. Gratton. GigaHertz photon density waves in a turbid medium: Theory and experiments. Phys. Rev. E. 53, 2307-2319 (1996).
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| − | J-205 Gratton, E., W. W. Mantulin, G. Weber, C. A. Royer, R. Reininger and R. W. C. Hansen. Fluorescence dynamics of biological systems using synchrotron radiation. Rev. Sci. Instrum. 66 (9), 1-7 (1996).
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| − | J-206 Fantini, S., M. A. Franceschini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, K. T. Moesta, P. M. Schlag, and M. Kaschke. Frequency-domain optical mammography: Edge effect corrections. Med. Phys. 23 (1), 149-157 (1996).
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| − | J-207 Berberan-Santos, M. N., J. Canceill, E. Gratton, L. Jullien, J.-M. Lehn, P. So, J. Sutin and B. Valeur. Multichromophoric cyclodextrins. 3. Investigation of dynamics of energy hopping by frequency-domain fluorometry. J. Phys. Chem. 100 15-20
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| − | (1996).
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| − | J-208 Koenig, K., P. T. C. So, W. W. Mantulin, and E. Gratton. Cell damage in two-photon microscopes In: Proc. SPIE 2926, Optical Biopsies and Microscopic Techniques. I. J. Bigio, W. S. Grundfest, H. Schneckenburger, K. Svanberg, P. M. Viallet, eds.
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| − | 172-176 (1996).
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| − | J-209 Koenig, K., P. T. C. So, W. W. Mantulin, B. J. Tromberg and E. Gratton. Two-photon excited lifetime imaging of autofluorescence in cells during UVA and NIR photostress. J. Microscopy 183, 197-204 (1996).
| |
| − | J-210 Bismuto, E., I. Sirangelo, G. Erace, and E. Gratton. Pressure-induced perturbation of apomyoglobin structure: Fluorescence studies on native and acidic compact forms. Biochemistry 35, 1173-1178, (1996).
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| − | J-211 Koenig, K., P. T. C. So, W. W. Mantulin, E. Gratton, T. Krasieva, M. W. Berns and B. J. Tromberg. Two-photon excited cellular autofluorescence induced by cw and femtosecond NIR microradiation. Proc. SPIE, Int. Soc. Opt. Eng., 2628 , 12-19
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| − | (1996).
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| − | J-212 Zolese, G., E. Giambanco, G. Curatola, R. Staffolani, E. Gratton, and R. Donato. Time-resolved fluorescence of S-100a protein: Effect of Ca2+, Mg2+ and unilamellar vesicles of egg phosphatidylcholine. Cell Calcium 20(6), 465-474 (1996).
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| − | J-213 Fantini, S., M. A. Franceschini and E. Gratton. Effective source term in the diffusion equation for photon transport in turbid media. Appl. Opt. 36(1) , 156-163 (1996).
| |
| − | J-214 Maier, J., S. Walker and E. Gratton. Frequency-domain optical spectroscopy and imaging of tissues. In Biomedical Optical Instrumentation and Laser-assisted Biotechnology. Course on Biomedical Optical Instrumentation and Laser-assisted
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| − | Biotechnology, Erice, Italy, Nov. 10-22, 1995. A. M. Verga Scheggi, S. Martellucci, A. N. Chester and R. Pratesi, eds., Vol. 325, pp. 121-142 (1996).
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| − | J-215 Fantini, S., M. A. Franceschini, G. Gaida, H. Jess, H. Erdl, W. W. Mantulin, E. Gratton, K. M. Moesta, P. M. Schlag and M. Kaschke. Contrast enhancement by edge effect corrections in frequency-domain optical mammography. OSA Trends in
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| − | Optics and Photonics on Advances in Optical Imaging and Photon Migration 2, R. R. Alfano and J. G. Fujimoto, eds., 160-163 (1996).
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| − | J-216 Jess, H., H. Erdl, K. T. Moesta, S. Fantini, M. A. Franceschini, E. Gratton, and M. Kaschke. Intensity modulated breast imaging: Technology and clinical pilot study results. OSA Trends in Optics and Photonics on Advances in Optical Imaging and
| |
| − | Photon Migration 2, R. R. Alfano and J. G. Fujimoto, eds., 126-129 (1996).
| |
| − | Gratton, G., M. Fabiani, P. Corballis, D. C. Hood, M. Goodman, J. Hirsch, K. Kim, D. Friedman and E. Gratton. Fast and localized event-related optical signals (EROS) in the human occipital cortex: Comparisons with the visual evoked potential and fMRI. Neuroimage 6, 168-180 (1997).
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| − | J-217 Fantini, S., M. A. Franceschini, and E. Gratton, Effective source term in the diffusion equation for photon transport in turbid media, Appl. Opt. 36, 156-163 (1997).
| |
| − | J-218 Dong, C. Y., P. T. C. So, C. Buehler and E. Gratton. Spatial resolution in scanning pump-probe fluorescence microscopy. Optik, 106(1) 7-14 (1997).
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| − | J-219 Gratton, E., S. Fantini, M. A. Franceschini, G. Gratton and M. Fabiani. Measurements of scattering and absorption changes in muscle and brain. Phil. Trans. R. Soc. London. B 352 , 727-735 (1997).
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| − | J-220 Franceschini, M. A., S. Fantini, A. Cerussi, B. Barbieri, B. Chance and E. Gratton. Quantitative spectroscopic determination of hemoglobin concentration and saturation in turbid medium: Analysis of the effect of water absorption.
| |
| − | J. of Biomedical Optics 2(2), 147-153 (1997).
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| − | J-221 Franceschini, M. A., K. T. Moesta, S. Fantini, G. Gaida, E. Gratton, H. Jess, W. W. Mantulin, M. Seeber, P. M. Schlag, and M. Kaschke. Frequency-domain techniques enhances optical mammography: Initial clinical results.
| |
| − | Proc. Natl. Acad. Sci. USA, 94, 6468-6473 (1997).
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| − | J-222 Masters, B. R., P. T. C. So, and E. Gratton. Multi-photon excitation fluorescence and spectroscopy of in vivo human skin. Biophys. J. 72, 2405-2412 (1997).
| |
| − | J-223 Barshtein. G., L. Bergelson, A. Dagan, E. Gratton and S. Yedgar, S. Membrane lipid order of human red cells is altered by physiological levels of hydrostatic pressure. Amer. J. Physiol., Heart and Circulatory Physiology, 272, H538-H543 (1997).
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| − | J-224 Koenig, K., P. T. C. So, W. W. Mantulin, and E. Gratton, Cell Damage in Two-Photon Femtosecond Microscopes, Applied Optics 22, 135 (1997).
| |
| − | J-225 Parasassi, T., E. Gratton, W. Yu, P. Wilson, and M. Levi. Two-photon fluorescence microscopy of laurdan gp-domains in model and natural membranes. Biophys. J. 72 (5), 2413-2429 (1997).
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| − | J-226 Cerussi, A., J. S. Maier, S. Fantini, M. A. Franceschini, W. W. Mantulin and E. Gratton. Experimental verification of a theory for the time-resolved fluorescence spectroscopy of thick tissues. Diffusing Photons in Turbid Media,
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| − | Appl. Opt. 36(1) , 116-124 (1997).
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| − | J-227 S. Fantini, K. T. Moesta, M. A. Franceschini, H. Jess, H. Erdl, E. Gratton, P. M. Schlag, and M. Kaschke, "Instrumentation and Clinical Applications in Frequency-Domain optical Mammography,"
| |
| − | Proc. 19th Int. Conf.-IEEE/EMBS on Photon Migration Tomography (MS21), A. H. Hielscher and L. Wang, chairs, pp. 2741-2744 (1997).
| |
| − | French, T., P. T. C. So, D. J. Weaver, Jr., T. Coelho-Sampaio, E. Gratton, E. W. Voss, Jr., and J. Carrero. Macrophage-mediated processing of an exogenous fluorescent antigenic probe. I. Use of processing probe with two photon fluorescence microscopy with time resolved and intensity imaging. J. Microscopy, 185 339-353 (1997).
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| − | J-228 Koenig, K., H. Liang, S. Kimel, O. Svaasand, B. J. Tromberg, T. b. Krasieva, M. W. Berns,K. J. Halbhuber, P. T. C. So, W. W. Mantulin, and E. Gratton, Cell damage in UVA and CW/Femtosecond NIR Microscopes. In Functional Imaging and
| |
| − | Optical Manipulation of Livings Cells, SPIE Proc. 2983, 37-44 (1997).
| |
| − | J-229 So, P. T. C., T Ragan, E. Gratton, J. Carrero, E, Voss. Two-photon Single Particle Tracking in 3-D. In Functional Imaging and Optical Manipulation of Livings Cells, SPIE Proc. 2983, 45-56 (1997).
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| − | J-230 So, P. T. C., K. H. Duggar, K. M. Berland and E. Gratton. Generating an Intracellular Diffusion Map by Two-photon Fluorescence Correlation Spectroscopy, In Material Science of the Cell, Symposium Material Research Society (1997).
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| − | J-231 Walker, S. A., S. Fantini and E. Gratton. Image reconstruction using back-projection from frequency domain optical measurements in highly scattering media. Appl. Opt. 36(1) , 170-179 (1997).
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| − | J-232 Bernsdorff, C., A. Wolf, R. Winter, and E. Gratton. Effect of hydrostatic pressure on water penetration and rotational dynamics in phospholipid-cholesterol bilayers. Biophys. J. 72, 1264-1277 (1997).
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| − | J-233 Cerussi, A. E., S. Fantini, J. S. Maier, W. W. Mantulin, and E. Gratton. Chromophore detection by fluorescence spectroscopy in tissue-like phantoms. SPIE Proc., Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model,
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| − | and Human Studies II, 2979 pp. 139-150 (1997).
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| − | J-234 Maier, J. S., A. E. Cerussi, S. Fantini, and E. Gratton. Experimental recovery of absorption, scattering, and fluorescence parameters in highly-scattering media from a single measurement. SPIE Proc., Optical Tomography and Spectroscopy of
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| − | Tissue: Theory, Instrumentation, Model, and Human Studies II, 2979 6-13 (1997).
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| − | J-235 Walker, S. A., S. Fantini, and E. Gratton. The effect of index of refraction mismatch on the recovery of optical properties of cylindrical inhomogeneities in an infinite turbid medium. SPIE Proc., Optical Tomography and Spectroscopy of Tissue:
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| − | Theory, Instrumentation, Model, and Human Studies II, 2979 219-225 (1997).
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| − | J-236 Franceschini, M. A., D. Wallace, B. Barbieri, S. Fantini, W. W. Mantulin, S. Pratesi, G. P. Donzelli and E. Gratton. Optical study of the skeletal muscle during exercise with a second generation frequency-domain tissue oximeter. SPIE Proc., Optical
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| − | Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model, and Human Studies II, 2979 807-814 (1997).
| |
| − | J-237 Fantini, S., M. A. Franceschini, and E. Gratton. Effect of spatially distributed light sources on the frequency-domain solution to the diffusion equation. SPIE Proc., Optical Tomography and Spectroscopy of Tissue: Theory, Instrumentation, Model,
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| − | and Human Studies II, 2979 807-814 (1997).
| |
| − | J-238 Franceschini, M. A., S. Fantini, L. A. Paunescu, J. S. Maier, and E. Gratton. Influence of a superficial layer in the quantitative spectroscopic study of strongly scattering media. Appl. Opt. 37, 7447-7458 (1998).
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| − | J-239 Masters, B.R., P. T. So, and E. Gratton. Multiphoton Excitation Microscopy of In Vivo Human Skin: Functional and Morphological Optical Biopsy Based on Three-Dimensional Imaging, Lifetime Measurements and Fluorescence Spectroscopy.
| |
| − | Annals of the New York Academy of Sciences. 838:58-67 (1998).
| |
| − | J-240 Chance B., M. Cope, E. Gratton, N. Ramanujam, and B. Tromberg. Phase measurement of light absorption and scatter in human tissue. Rev. of Sci. Inst. 69 (10), 3457-3481, (1998).
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| − | J-241 Di Venere, A., G. Mei, G. Gilardi, N. Rosato, F. De Matteis, R. McKay, E. Gratton, and S. Finazzi-Agró. Resolution of heterogeneous fluorescence in multi-tryptophan proteins: ascorbate oxidase. Eur. J. Biochem. 257, 337-343, (1998).
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| − | J-242 Walker, S. A., D. A. Boas, and E. Gratton. Photon density waves scattered from cylindrical inhomogeneities: Theory and experiments. Appl. Opt. 37(10), 1935-1944 (1998).
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| − | J-243 Krasnowska, E., K., E. Gratton, and T. Parasassi. Prodan as a membrane surface fluorescence probe. Partitioning between water and phospholipid phases. Biophys. J. 74: 1984-1993 (1998).
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| − | J-244 Bagatolli, L. A., E. Gratton and G. D. Fidelio. Water dynamics in glysophingolipid aggregates studied by Laurdan fluorescence. Biophys. J. 75:331-341 (1998).
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| − | J-245 Parasassi, T., E. K. Krasnowska, L. Bagatolli, and E. Gratton. Laurdan and prodan as polarity-sensitive fluorescent membrane probes. J. of Fluorescence 8 (4), 365-373 (1998).
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| − | J-246 Toronov, V., M. Filiaci, S. Fantini, and E. Gratton. Photon-density wave correlation spectroscopy detects large-scale fluctuations in turbid media. Phys. Rev. E. 58, 2288-2297 (1998)
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| − | J-247 Fantini, S., S. A. Walker, M. A. Franceschini, K. T. Moesta, P. M. Schlag, M. Kaschke, and E. Gratton. Assessment of the size, position, and optical properties of breast tumors in vivo by noninvasive optical methods, Appl. Opt. 37, 1982-1989
| |
| − | (1998).
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| − | J-248 So, P. T. C., K. Koenig, K. M. Berland, C. Y Dong, T. French, C. Buehler, T. Ragan, and E. Gratton. New Time-resolved Techniques in Two-photon Microscopy, Cell. Mol. Biol. 44, 771-773 (1998).
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| − | J-249 Masters, B. R., P. So, E. Gratton, Optical Biopsy of In vivo human skin: Multi-photon excitation microscopy, Lasers in Medical Science 13, 197-204 (1998).
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| − | J-250 Kim, K. H., P. T. C. So, I. E. Kochevar, B. R. Masters, and E. Gratton, Two-photon fluorescence and confocal reflected light imaging of thick tissue structures, SPIE Proc. 3260, Eds., D. L. Farkas, R. C. Leif, and B. J. Tromberg, 46-57 (1998).
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| − | J-251 Franceschini, M. A., S. Fantini, R. Palumbo, L. Pasqualini, G. Vaudo, E. Franceschini, E. Gratton, B. Palumbo, S. Innocente and E. Mannarino. Quantitative near-infrared spectroscopy on patients with peripheral vascular disease. In: Proc. SPIE
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| − | 3194 (BIOS Europe '97, San Remo, Italy, Sept. 4-8) 112-115 (1998).
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| − | J-252 Quaresima, V., M. A. Franceschini, S. Fantini, E. Gratton and M. Ferrari. Difference in leg muscles oxygenation during treadmill exercise by a new near infrared frequency-domain oximeter. In: Proc. SPIE 3194 (BIOS Europe '97, San Remo, Italy,
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| − | Sept. 4-8) 116-120 (1998).
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| − | J-253 Toronov, V., M. Filiaci, M. Franceschini, S. Fantini, and E. Gratton. Exploring tissue dynamics by photon-density-wave fluctuation correlation spectroscopy, Proc. SPIE 3726, Eds., Tuchin, Ryabukho, Zimnyakov, pp. 555-559 (1999).
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| − | J-254 Cerussi, A. E., E. Gratton, and S. Fantini, Fluorescence lifetime spectroscopy in multiple-scattering environments: An application to biotechnology, SPIE Proc. 3600, Eds., Bornhop, Contag, and Sevick, pp. 171-181, (1999)
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| − | J-255 Casavola, C., L. A. Paunescu, S. Fantini, M. A. Franceschini, P. M. Lugara, and E. Gratton. Application of near-infrared tissue oximeter to the diagnosis of peripheral vascular disease. Clinical Hemorheology and Microcirculation 21, 389-393
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| − | (1999).
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| − | J-256 Nayfeh, M., O. Akcakir, J. Theiren, Z. Yamani, N. Barry, W. Yu and E. Gratton. Highly nonlinear photoluminescence threshold in porous silicon, Appl. Phys. Lett. 75 4112 (1999).
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| − | J-257 Bagatolli, L. A., T. Parasassi, G.D. Fidelio, and E. Gratton. A model for the interaction of 6-Lauroyl2-(N,N-dimethylamino)naphthalene with lipid environments: Implications for spectral properties. Photochem. and Photobiol. 70 (4), 557-564
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| − | (1999).
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| − | J-258 Bagatolli, L. A. and E. Gratton. Two-photon fluorescence microscopy observation of shape changes at the phase transition in phospholipid's giant unilamellar vesicles. Biophys. J. 77, 2090-2101 (1999).
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| − | Stankovic, M. R., D. Maulik, W. Rosenfeld, P. G. Stubblefield, A. D. Kofinas, S. Drexler, R. Nair, M. A. Franceschini, D. Hueber, E. Gratton, and S. Fantini, Real-Time Optical Imaging of Experimental Brain Ischemia and Hemorrhage in Neonatal Piglets, J. Perinat. Med. 27 (4) 279-286 (1999).
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| − | J-259 Fantini, S., D. Hueber, M. A. Franceschini, E. Gratton, W. Rosenfeld, P. G. Stubblefield, D. Maulik, and M. R. Stankovic. Noninvasive optical monitoring of the newborn piglet brain using continuous-wave and frequency-domain spectroscopy.
| |
| − | Physics in Med. and Biol. 44(6), 1543-63 (1999).
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| − | J-260 Franceschini, M. A., E. Gratton, and S. Fantini. Noninvasive optical method of measuring tissue and arterial saturation: an application to absolute pulse oximetry of the brain. Opt. Lett. 24 (12), 829-831, (1999).
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| − | J-261 Chen, Y., J. D. Müller, P. T. C. So, and E. Gratton, The Photon Counting Histogram in Fluorescence Fluctuation Spectroscopy, Biophys. J. 77: 553-567 (1999).
| |
| − | J-262 Buehler, C., K. H. Kim, B. R. Masters, P. T. C. So, I. E. Kochevar, and E. Gratton, Two-photon Deep Tissue Imaging, IEEE Engineering in Medicine and Biology 18, 23-30 (1999).
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| − | J-263 Masters, B. R., P. T. C. So, and E. Gratton, Multiphoton excitation microscopy and confocal microscopy of human skin in vivo, Comments on Cell. and Mol. Biophys. 9(6), 379-405 (1999).
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| − | J-264 Masters, B. R., P. T. C. So, K. H. Kim, C. Buehler, and E. Gratton. Multiphoton Excitation microscopy, Confocal Microscopy, and Spectroscopy of Living Cells and Tissues; Functional Metabolic Imaging of Human Skin In Vivo, Methods Enzymol,
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| − | 307, 513-536 (1999).
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| − | J-265 Masters, B. R., P. T. C. So, E. Gratton, G. Gonnord, P. Corcuff, Microscopy of Human Skin In Vivo: Multi-photon Excitation and Confocal Microscopy, Microscopy and Microanalysis 5, 282-289 (1999).
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| − | J-266 Parasassi, T., E. Gratton, H. Zajicek, M. Levi, and W. Yu. Detecting membrane lipid microdomains by two-photon fluorescence microscopy. IEEE Engineering in Medicine and Biology 18 (5), 92-99, (1999).
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| − | J-267 Fantini, S., M. A. Franceschini, E. Gratton, D. Hueber, W. Rosenfeld, D. Maulik, P. G. Stubblefield, and M. R. Stankovic. Non-invasive optical mapping of the piglet brain in real time. Opt. Express 4 (8), 308-314 (1999).
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| − | J-268 Franceschini, M. A., E. Gratton, D. Hueber, and S. Fantini. Near-Infrared Absorption and Scattering Spectra of Tissues in Vivo. SPIE Biomedical Optics '99, San Jose (CA) Vol. 3597, 526-531 (1999).
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| − | J-269 Filiaci, M., M. A. Franceschini, S. Fantini, and E. Gratton. Photon density waves in tissues: a study of the optical properties during changes in the oxygenation level. SPIE Biomedical Optics '99, San Jose (CA) Vol. 3597 (1999).
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| − | J-270 Stankovic, M. R., , D. M. Hueber, D. Maulik, P, G. Stubblefield, W. Rosenfeld, E. Gratton, M. A. Franceschini, and S. Fantini. Real-Time Optical Imaging and Spectroscopy of Brain Ischemia and Hemorrhage. SPIE Biomedical Optics '99,
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| − | San Jose (CA) Vol. 3597 (1999).
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| − | J-271 Toronov, V., M. Filiaci, M. A. Franceschini, S. Fantini, and E. Gratton. Photon-density-wave fluctuation-correlation-spectroscopy: study of coherence in the brain and muscles. SPIE Biomedical Optics '99, San Jose (CA) Vol. 3597 (1999).
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| − | J-272 Lasagna, M., E. Gratton, D. M. Jameson, and J. E. Brunet. Apohorseradish peroxidase unfolding and refolding: Intrinsic tryptophan fluorescence studies. Biophys. J. 76: 443-450 (1999).
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| − | J-273 Paunescu, L. A., C. Casavola, M. A. Franceschini, S. Fantini, L. Winter, J. Kim, D. Wood and E. Gratton. Calf muscle blood flow and oxygen consumption measured with near-infrared spectroscopy during venous occlusion. SPIE Proc. 3597,
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| − | Eds., B. Chance, R. R. Alfano, B. J. Tromberg, pp. 317323 (1999).
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| − | J-274 Casavola, C., L. A. Paunescu, M. A. Franceschini, S. Fantini, L. Winter, J. Kim, D. Wood, and E. Gratton. Near-infrared spectroscopy and the tilting table protocol: a novel method to study the blood flow and the oxygen consumption in tissues.
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| − | SPIE Proc. 3597, Eds., Britton Chance, Robert R. Alfano, and Bruce J. Tromberg, pp. 685-692 (1999).
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| − | J-275 Buehler, C., C. Y. Dong, P. T. C. So, T. E. French, and E. Gratton. Frequency-domain pump-probe microscopic imaging using intensity-modulated laser diodes In: Proc. SPIE 3603, Systems and Technologies for Clinical Diagnostics and Drug
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| − | Discovery II. G. E. Cohn, J. C. Owicki, eds., 262271 (1999).
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| − | J-276 Franceschini, M. A., S. Fantini, V. Toronov, M. E. Filiaci, and E. Gratton. Cerebral hemodynamics measured by near-infrared spectroscopy at rest and during motor activation. In Proc. Inter-Institute Workshop on In Vivo Optical Imaging at the
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| − | NIH, OSA pp. 73-80 (2000).
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| − | J-277 Bettati, S., S. Benci, B. Campanini, S. Raboni, G. Chirico, S. Beretta, K. D. Schnackerz, T. L. Hazlett, E. Gratton, and A. Mozzarelli. Role of pyridoxal 5'-phosphate in the structural stabilization of 0-acetylserine sulfhydrylase.
| |
| − | J. Biolog. Chem. 275(51), 40244-40251 (2000).
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| − | J-278 Arcangeli, C., W. Yu, S. Cannistraro, and E. Gratton. Two-photon autofluorescence microscopy and spectroscopy of an Antarctic fungus: a new approach for studying the effect of UV-B irradiation, Biospectroscopy 57(4) 218-225 (2000).
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| − | Zolese, G., G. Falcioni, E. Bertoli, R. Galeazzi, M. Wozniak, Z. Wypych, E. Gratton, and A. Ambrosini. Steady-state and time resolved fluorescence of albumins interacting with noleylethanolamine, a component of the endogenous n-acylethanolamines. Proteins: Structure, Function, and Genetics 40, 39-40 (2000).
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| − | J-279 Stankovic M. R., D. Maulik, W. Rosenfeld, P. G. Stubblefield, A. D. Kofinas, E. Gratton, M. A. Franceschini, S. Fantini, D. Hueber.
| |
| − | The role of frequency domain optical spectroscopy in the detection of neonatal brain hemorrhage - a newborn piglet study. J Maternal Fetal Medicine 9(2), 142-149 (2000).
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| − | J-280 Chen, Y., J. D. Müller, S. Y Tetin, J. D. Tyner and E. Gratton. Probing ligand protein binding equilibria with fluorescence fluctuation spectroscopy. Biophys. J. 79(2), 1074-1084 (2000).
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| − | J-281 Casavola, C,. L. A. Paunescu, S. Fantini, M. A. and E. Gratton. Blood flow and oxygen consumption with near-infrared spectroscopy and venous occlusion: Spatial maps and the effect of time and pressure of inflation.
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| − | J. of Biomedical Optics 5(3), 269-276 (2000).
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| − | J-282 Parasassi, T., W. Yu, D. Durbin, L. Kuriashkina, E. Gratton, N. Maeda and F. Ursini. Two-photon microscopy of aorta fibers shows proteolysis induced by LDL hydroperoxides. Free Radical Biology and Medicine 28(11), 1589-1597 (2000).
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| − | J-283 Bagatolli, L. A., and E. Gratton, A correlation between lipid domain shape and binary phospholipid mixture composition in free standing bilayers. A two-photon fluorescence microscopy study, Biophys. J. 79, 434-447 (2000).
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| − | J-284 Bagatolli, L., E. Gratton, T. K. Khan, and P. L-G. Chong. Two-photon fluorescence microscopy studies of bipolar tetraether giant liposomes from thermoacidophilic archaebacteria sulfolobus acidocaldarius, Biophys. J. 79(1), 416-425 (2000).
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| − | J-285 Buehler, C., C. Y. Dong, P. T. So., T. French, and E. Gratton. Time-resolved polarization imaging by pump-probe (stimulated emission) fluorescence microscopy. Biophys. J. 79, 536-549 (2000).
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| − | J-286 Sukhishvili, S A., Y. Chen, J.D.. Muller, E. Gratton, K.S. Schweizer, S. Granick. Materials science: Diffusion of a polymer 'pancake'. Nature. 406(6792):146 (2000).
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| − | J-287 Eid, J., J. D. Müller, and E. Gratton. Data acquisition card for FCS allowing full access to the detected photon sequence. Rev. of Sci. Inst. 71(2), 361-368 (2000).
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| − | J-288 Bagatolli, L. A., T. Parasassi, and E. Gratton. Giant phospholipid vesicles: comparison among the whole lipid samples characteristics using different preparation methods. A two-photon fluorescence microscopy study, Chemistry and Physics of
| |
| − | Lipids 105, 135-147 (2000).
| |
| − | J-289 Fantini, S. and E. Gratton. Fluorescence photon-density waves in optically diffusive media. Optics Communications 173, 73-79 (2000).
| |
| − | J-290 Franceschini, M. A., V. Toronov, M. Filiaci, E. Gratton, and S. Fantini. On-line optical imaging of the human brain with 160-ms temporal resolution, Optics Express 6(3), 49-57 (2000).
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| − | J-291 Frolov, A., A. Petrescu, B. P. Atshaves, P. T. C. So, E. Gratton, G. Serrero and F. Schroeder.
| |
| − | High Density Lipoprotein-mediated Cholesterol Uptake and Targeting to Lipid Droplets in Intact L-cell Fibroblasts. A Single- and Multiphoton Fluorescence Approach. J. Biol. Chem. 275, 12769-12780 (2000).
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| − | J-292 Müller, J. D., Y. Chen, and E. Gratton. Resolving heterogeneity on the single molecular level with the photon counting histogram. Biophys. J. 78(1) 474-486 (2000).
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| − | J-293 Bagatolli, L. A. and E. Gratton. Two photon fluorescence microscopy of coexisting lipid domains in giant unilamellar vesicles of binary phospholipid mixtures. Biophys. J., 78 290-305 (2000).
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| − | J-294 Michalos, A., L. A. Paunescu, M. Wolf, U. Wolf, V. Toronov, M. A. Franceschini, S. Fantini, and E. Gratton. Assessment of cerebral oxygenation and hemodynamics in obstructive sleep apnea syndrome. SuH16, Proc. OSA Technical Digest,
| |
| − | Biomedical Topical Meeting (2000)
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| − | J-295 Toronov, V., M. A. Franceschini, M. Filiaci, S. Fantini, M. Wolf, A. Michalos, and E. Gratton. Near-infrared study of fluctuations in cerebral hemodynamics during rest and motor stimulation: Temporal analysis and spatial mapping,
| |
| − | Med. Phys. 27(4), 801-815 (2000).
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| − | J-296 Franceschini, M. A., S. Fantini, V. Toronov, M. E. Filiaci, M. P. Wolf, A. Michalos, and E. Gratton. Real-time video of brain activation in human subjects using a non-invasive near-infrared technique. ME6, Proc. OSA Technical Digest,
| |
| − | Biomedical Topical Meeting (2000).
| |
| − | J-297 Paunescu, L. A., U. Wolf, M. Wolf, A. Michalos, and E. Gratton. Scattering coefficient-hemoglobin concentration relation determined by frequency-domain spectroscopy during venous occlusion. TuD2. Proc. OSA Technical Digest,
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| − | Biomedical Topical Meeting (2000).
| |
| − | J-298 Wolf, M., V. Toronov, U. Wolf, L. A. Paunescu, A. Michalos, and E. Gratton. Maps of cerebral hemoglobin concentration changes obtained by near-infrared spectroscopy, Characterization of phase shifts among locations. TuF6, Proc.
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| − | OSA Technical Digest, Biomedical Topical Meeting, pp. 416418 (2000).
| |
| − | J-299 Wolf, U., M. Wolf, V. Toronov, A. Michalos, L. A. Paunescu, and E. Gratton. Detecting cerebral functional slow and fast signals by frequency-domain near-infrared spectroscopy using two different sensors. TuF10, Proc. OSA Technical Digest,
| |
| − | Biomedical Topical Meeting, pp. 427-429 (2000).
| |
| − | J-300 Toronov, V., M. Wolf, A. Michalos, and E. Gratton. Analysis of cerebral hemodynamic fluctuations measured simultaneously by magnetic resonance imaging and near-infrared spectroscopy. WA5, Proc. OSA Technical Digest, Biomedical Topical
| |
| − | Meeting (2000).
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| − | J-301 Akcakir, O., J. Theiren, N. Barry, M. Nayfeh and E. Gratton. Detection of luminescent single ultra small silicon nanoparticles using fluctuation correlation spectroscopy, Appl. Phys. Lett. 76, 14 (2000).
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| − | J-302 Toronov V, Fantini S, Franceschini MA, Filiaci M, Wolf M, Gratton E. Temporal analysis of fluctuations in cerebral hemodynamics revealed by near-infrared spectroscopy. In: Proc. SPIE 4001, Saratov Fall Meeting '99: Optical Technologies in
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| − | Biophysics and Medicine. V. V. Tuchin, D. A. Zimnyakov, A. B. Pravdin, eds., 224-227 (2000).
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| − | J-303 Huang, H. C. Y. Dong, J. D. Sutin, H. S. Kwon, G. Cragg, R. Gilbert, R. T. Lee, E. Gratton, R. D. Kamm, D. Lauffenburger, and P. T. So. Magnetic tweezers microscope for cellular manipulation In: Proc. SPIE 3921, Optical Diagnostics of Living
| |
| − | Cells III. D. L. Farkas, R. C. Leif, eds., 176-185 (2000).
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| − | J-304 Wolf, M., M. A. Franceschini, L. A. Paunescu, V. Toronov, A. Michalos, U. Wolf, E. Gratton, and S. Fantini. Absolute frequency-domain pulse oxymetry of the brain: Methodology and measurements. In: Proc. ISOTT Oxygen Transport to Tissue
| |
| − | XXII. 27th Annual Meeting of ISOTT, J. F. Dunn, H. M. Swartz, eds. (2000).
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| − | J-305 Toronov, V., A. Webb, J-H. Choi, M. Wolf, and E. Gratton. Simultaneous assessment of human brain functional hemodynamics by magnetic resonance and near-infrared imaging. In: Proc. SPIE 4320, Medical Imaging 2001: Physics of Medical
| |
| − | Imaging. L. E. Antonuk, M. J. Yaffe, eds., 861-867 (2001).
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| − | J-306 Toronov, V. Y., A. G. Webb, J. H. Choi, M. Wolf, L. P. Safonova, U. Wolf, E. Gratton. Functional cerebral activation detected by frequency-domain near-infrared spectroscopy. In: Proc. SPIE, Optical Technologies in Biophysics and Medicine III;
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| − | Saratov Fall Meeting, V. V. Tuchin; ed., Vol. 4707, 92-96 (2001).
| |
| − | J-307 Sanchez, S. A., Y. Chen, J. D. Mueller, E. Gratton, T. L. Hazlett. Solution and interface aggregation states of C. atrox venom phospholipase A2 by 2-photon excitation fluorescence correlation spectroscopy. Biochemistry 40, 6903-6911 (2001).
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| − | J-308 Bagatolli, L. A., and E. Gratton. Direct observation of lipid domains in free standing bilayers using two-photon excitation fluorescence microscopy. J. of Fluorescence 11(3), 141-160 (2001).
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| − | J-309 Bismuto, E., E. Gratton, and D. C. Lamb. Dynamics of ANS Binding to Tuna Apomyoglobin Measured with Fluorescence Correlation Spectroscopy. Biophys. J. 81, 3510-3521 (2001).
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| − | J-310 Gratton, E., N. P. Barry, S. Beretta and A. Celli. Multiphoton Fluorescence Microscopy. Methods 25(1), 103-110 (2001).
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| − | J-311 Toronov, V., A. Webb, J-H. Choi, M. Wolf, L. Safonova, U. Wolf and E. Gratton.
| |
| − | Study of local cerebral hemodynamics by frequency-domain near-infrared spectroscopy and correlation with simultaneously acquired functional magnetic resonance imaging. Optics Express 9(8), 417-427 (2001).
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| − | J-312 Krasnowska, E. K., L. A. Bagatolli, E. Gratton and T. Parasassi. Surface properties of cholesterol-containing membranes detected by Prodan fluorescence. BBA - Biomembranes 1511(2) 330-340 (2001).
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| − | J-313 Van Rompaey, E., Y. Chen, J. D. Mueller, E. Gratton, E. Van Craenenbroeck, Y. Engelborghs, S. De Smedt and J. Demeester. Fluorescence fluctuation analysis for the study of interactions between oligonucleotides and polycationic polymers.
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| − | Biological Chem. 382, 379-386 (2001).
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| − | J-314 Margeat, E., N. Poujol, A. Boulahtouf, Y. Chen, J. D. Muller, E. Gratton, V. Cavailles, and C. Royer. The Human estrogen receptor a dimer binds a single SRC-1 coactivator molecule with an affinity dictated by agonist structure.
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| − | J. Mol. Biol. 306 (3), 433-442 (2001).
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| − | J-315 Toronov, V., A. Webb, J. H. Choi, M. Wolf, A. Michalos, E. Gratton and D. Hueber. Investigation of human brain hemodynamics by simultaneous near-infrared spectroscopy and functional magnetic resonance imaging. Medical Physics 28(4)
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| − | 521-527 (2001).
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| − | J-316 Chirico, G., S.Bettati, A. Mozzarelli, Y. Chen, J. D.Müller, and E. Gratton. Molecular Heterogeneity of O-Acetylserine Sulfhydrylase by Two-Photon Excited Fluorescence Fluctuation Spectroscopy. Biophys J. 80(4), 1973-1985 (2001).
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| − | J-317 Dietrich, C., L. A. Bagatolli, Z. N. Volovyk, N. L. Thompson, M. Levi, K. Jacobson, and E. Gratton. Lipid Rafts Reconstituted in Model Membranes. Biophys. J. 80(3), 1417-1428 (2001).
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| − | J-318 Dong, C-Y, C. Buehler, P. T. C. So, T. French, and E. Gratton. Implementation of intensity-modulated laser diodes in time-resolved, pump-probe fluorescence microscopy. Appl. Opt. 40, 1109-1115 (2001).
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| − | J-319 Barcellona, M. L., Y. Chen, J. D. Müller, and E. Gratton. 4',6-diamidino-2-phenylindole (DAPI) interacts with rare structures of GC polymers. Eur. Biophys. J. 30 (2), 98-109 (2001).
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| − | J-320 Nayfeh, M. H., J. Therrien, G. Belomoin, A. Akcakir, N. Barry, and E. Gratton. Stimulated blue emission and second harmonic generation from films of ultrasmall Si nanoparticles. In: Proc. Materials Research Society Symposium, V. 638 F951-
| |
| − | F9512 (2001).
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| − | J-321 Ragan, T., P. T. C. So, H-S.Kwon, and E. Gratton. 3D particle tracking on the two-photon microscope In: Proc. SPIE 4262, Multiphoton Microscopy in the Biomedical Sciences. A. Periasamy, P. T. So, eds., 247-258 (2001).
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| − | J-322 Toronov, V., A. Webb, J. H. Choi, M. Wolf, E. Gratton, and D. M. Hueber. Simultaneous functional magnetic resonance and near-infrared imaging of adult human brain. In: Proc. SPIE 4250, Optical Tomography and Spectroscopy of Tissue IV.
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| − | B. Chance, R. R. Alfano, B. J. Tromberg, M. Tamura, E. M. Sevick-Muraca, eds. 380-382 (2001).
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| − | J-323 Paunescu, L. A., A. Michalos, J. H. Choi, U. Wolf, M. Wolf, and E. Gratton. In vitro correlation between reduced scattering coefficient and hemoglobin concentration of human blood determined by near-infrared spectroscopy.
| |
| − | In: Proc. SPIE Proc. 4250, BIOS 2001; Internatonal Biomedical Optics Symposium. Optical Tomography and Spectroscopy of Tissue IV. B.Chance, R.R. Alfano, B.J. Tromberg, M. Tamura, E.M. Sevick-Muraca, eds., 319-326 (2001).
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| − | J-324 Ruan, Q., Y. Chen, E. Gratton, M. Glaser and W. W. Mantulin. Cellular characterization of adenylate kinase and its isoform; Two-photon excitation fluorescence imaging and fluorescence correlation spectroscopy. Biophys. J. 83 (6), 3177-3187
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| − | (2002).
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| − | J-325 Hanson, K.M., M. J. Behne, N. P. Barry, T. M. Mauro, E. Gratton, and R. M. Clegg. Two-photon fluorescence lifetime imaging of the skin stratum corneum pH gradient. Biophys J. 83(3), 1682-1690 (2002).
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| − | J-326 Wolf, M., U. Wolf, J.H. Choi, R. Gupta, L. P. Safonova, L. A. Paunescu, A. Michalos and E. Gratton. Functional Frequency-Domain Near-Infrared Spectroscopy Detects Fast Neuronal Signal in the Motor Cortex,
| |
| − | NeuroImage 17(4), 1868-1875 (2002).
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| − | J-327 Wolf, M., U. Wolf, V. Toronov, A. Michalos, L. A. Paunescu, J-H. Choi and E. Gratton.
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| − | Different time evolution of oxyhemoglobin and deoxyhemoglobin concentration changes in the visual and motor cortices during functional stimulation: A near-infrared spectroscopy study. NeuroImage 16, 704-712 (2002).
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| − | J-328 Bettati, S., B.Campanini, S. Vaccari, A. Mozzarelli, G. Schianchi, T. L. Hazlett, and E. Gratton. Unfolding of pyridoxal 5'-phosphate-dependent O-acetylserine sulfhydrylase probed by time-resolved tryptophan fluorescence. Biochim. Biophys. Acta
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| − | 1596(1), 47-54 (2002).
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| − | J-329 Tricerri, M A., S. A. Sanchez, C. Arnulphi, D. M. Durbin, E. Gratton, A. Jonas. Interaction of apolipoprotein A-I in three different conformations with palmitoyl oleoyl phosphatidylcholine vesicles, J. of Lipid Research 43(2), 187-197 (2002).
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| − | J-330 Patel, R. C; U. Kumar, D. C. Lamb, J. S. Eid, M. Rocheville, M. Grant, A. Rani, T. Hazlett, S. C. Patel, E. Gratton, Y. C. Patel. Ligand binding to somatostatin receptors induces receptor-specific oligomer formation in live cells. Proc. of the National
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| − | Academy of Sciences of the USA 99(5), 32943299 (2002).
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| − | J-331 Fahsel, S., E.-M. Pospiech, M. Zein, T. L. Hazlet, E. Gratton, and R. Winter. Modulation of Concentration Fluctuations in Phase-Separated Lipid Membranes by Polypeptide Insertion. Biophys. J. 83, 334-344 (2002).
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| − | J-332 Behne, M.J., J. W. Meyer, K. M. Hanson, N. P. Barry, S. Murata, D. Crumrine, R. W. Clegg, E. Gratton, W. M. Holleran, P. M. Elias, and T. M. Mauro.
| |
| − | NHE1 regulates the stratum corneum permeability barrier homeostasis. Microenvironment acidification assessed with fluorescence lifetime imaging. J Biol Chem. 277(49):47399-47406 (2002).
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| − | J-333 Sanchez, S.A., L. A. Bagatolli, E. Gratton, and T. L. Hazlett. A Two-Photon View of an Enzyme at Work: Crotalus atrox Venom PLA2 Interaction with Single-Lipid and Mixed-Lipid Giant Unilamellar Vesicles. Biophys. J. 82, 2232-2243 (2002).
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| − | J-334 Chen, Y., J. D. Müller, Q.Q. Ruan, and E. Gratton. Molecular Brightness Characterization of EGFP in Vivo by Fluorescence Fluctuation Spectroscopy. Biophys. J. 82, 133-144 (2002).
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| − | J-335 Sukhishvili, S. A., Y. Chen, J.D. Muller, E. Gratton, K. S. Schweizer, S. Granick. Surface Diffusion of Poly(ethylene glycol). Macromolecules 35(5), 1776-1784 (2002).
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| − | J-336 Barry, N. P., K. M. Hanson, E. Gratton, R. M. Clegg, M. J. Behne, and T. Mauro. Applications of ultrafast lasers to two-photon fluorescence and lifetime imaging. In: Proc. SPIE 4633, Commercial and Biomedical Applications of Ultrafast and Free-
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| − | Electron Lasers. G. S. Edwards, J. Neev, A. Ostendorf, J. C. Sutherland, eds., 50-61 (2002).
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| − | J-337 Morren, G., M. Wolf, P. Lemmerling, U. Wolf, J. H. Choi, E. Gratton, L. De Lathauwer, and S. Van Huffel.
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| − | Extraction of fast neuronal changes from multichannel functional near-infrared spectroscopy signals using independent component analysis. In: Proc. SPIE 4623 , Functional Monitoring and Drug-Tissue Interaction. M. D. Kessler, G. J. Mueller;
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| − | eds., 68-76 (2002).
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| − | J-338 Toronov, V., E. D'Amico, D. Hueber, E. Gratton, B. Barbieri, A.Webb. Optimization of the signal-to-noise ratio of frequency-domain instrumentation for near-infrared spectro-imaging of the human brain. Optics Express 11(21), 2717-2729 (2003).
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| − | J-339 Levi, V., Q. Ruan, K. Kis-Petikova and E. Gratton. Scanning FCS, a novel method for three-dimensional particle tracking. Biochem. Soc. Transactions 31(5), 997-1000 (2003).
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| − | J-340 Toronov, V., A. Webb, S. Walker, R. Gupta, J. H. Choi, E. Gratton, and D. M. Hueber. Study of the FMRI blood oxygen level dependent effect by near-infrared spectroscopy. In: Proc. SPIE Int. Soc. Opt. Eng. 5068, 222 (2003).
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| − | J-341 Gratton, E., Scanning FCS: measuring spatio-temporal correlations in the millisecond range. In: Proc. SPIE, Vol. #4963, San Jose, CA (2003).
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| − | J-342 Gaus, K., E. Gratton, E. P. W. Kable, A. S. Jones, I. Gelissen, L. Kritharides, and W. Jessup. Visualizing lipid structure and raft domains in living cells with two-photon microscopy. Proc. Nat. Acad. Sci. 100, 15554-15559 (2003).
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| − | J-343 Muller, J. D. and E. Gratton. High-pressure fluorescence correlation spectroscopy. Biophys. J. 85, 2711-2719 (2003).
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| − | J-344 Wolf, U., M. Wolf, J. H. Choi, M. Levi, D. Choudhury, S. Hull, D. Coussirat, L. A. Paunescu, L. P. Safonova, A. Michalos, W. W. Mantulin and E. Gratton.
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| − | Localized irregularities in hemoglobin flow and oxygenation in the calf muscle in patients with peripheral vascular disease detected by near-infrared spectrophotometry. J. Vasc. Surgery 37, 1017-1026 (2003).
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| − | J-345 Toronov. V. S. Walker, R. Gupta, J. H. Choi, E. Gratton, D. Hueber and A. Webb. The roles of changes in deoxyhemoglobin concentration and regional cerebral blood volume in the fMRI BOLD signal. NeuroImage 19 (4), 1521-1531(2003).
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| − | J-346 Gratton, E., S. Breusegem, J. Sutin, Q. Ruan and N. Barry. Fluorescence lifetime imaging for the two-photon microscope: Time-domain and frequency-domain methods. J. of Biomedical Optics 8(3), 381-390 (2003).
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| − | J-347 Wolf, M., M.A. Franceschini, L.A. Paunescu, V. Toronov, A. Michalos, U. Wolf, E. Gratton and S. Fantini. Absolute frequency-domain pulse oximetry of the brain: Methodology and measurements. Adv Exp Med Biol. 530: 61-73 ( 2003).
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| − | J-348 Behne, M. J. N.P. Barry, K. M. Hanson, I. Aronchik, R. W. Clegg, E. Gratton, K. Feingold, W. M. Holleran, P.M. Elias, T.M. Mauro.
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| − | Neonatal development of the Stratum Corneum pH gradient: localization and mechanisms leading to emergence of optimal barrier function. J of Invest. Dermatology. 120(6), 998-1006, 2003.
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| − | J-349 Wolf, M., U. Wolf J.H. Choi, V. Toronov, L. A. Paunescu, A. Michalos, and E. Gratton. Fast cerebral functional signal in the 100ms range detected in the visual cortex by frequency-domain near-infrared spectroscopy.
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| − | Psychophysiology 40, 521-528 (2003).
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| − | J-350 Wolf, M., U. Wolf, J. H. Choi, R. Gupta, L. P. Safonova, L. A. Paunescu, A. Michalos and E. Gratton. Detection of the fast neuronal signal on the motor cortex using functional frequency domain near infrared spectroscopy.
| |
| − | Adv. Exp. Med. Biol. 510, D. F. Wilson, S. M. Evans, J. Biaglow, A. Pastuszko, eds., 193-197 (2003).
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| − | J-351 Wolf, U., M. Wolf, J. H. Choi, L. A. Paunescu, A. Michalos, L. Safonova and E. Gratton. Mapping of hemodynamics with near infrared spectroscopy of the human calf tissue and the influence of the adipose tissue thickness.
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| − | Adv. Exp. Med. Biol. D. F. Wilson, S. M. Evans, J. Biaglow, A. Pastuszko, eds., 225-230 (2003).
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| − | J-352 Best, K. B., A. J. Ohran, A. C. Hawes, T. L. Hazlett, E. Gratton, A. M. Judd, and J. D. Bell. Relationship between erythrocyte membrane phase properties and susceptibility to secretory phospholipase A2. Biochemistry 41(47), 13982-13988 (2003).
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| − | J-353 Zamai, M., M. VandeVen, M. Farao, E. Gratton, A. Ghiglieri, M. G. Castelli, E. Fontana, R. D'Argy, A. Fiorino, E. Pesenti, A. Suarato, V. R. Caiolfa.
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| − | Camptothecin poly[n-(2-hydroxypropyl) methacrylamide] copolymers in antitopoisomerase-I tumor therapy: intratumor release and antitumor efficacy. Mol Cancer Ther. 2(1), 29-40 (2003).
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| − | J-354 Safonova L.P., A. Michalos, U. Wolf, M. Wolf, W.W. Mantulin, D.M. Hueber and E. Gratton. Diminished cerebral circulatory autoregulation in obstructive sleep apnea investigated by near-infrared spectroscopy. Sleep Research On-line 5(4), 126-
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| − | 132 (2003).
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| − | J-355 Barcellona, M. L., S. Gammon, T. Hazlett, M. Digman and E. Gratton. Polarized fluorescence correlation spectroscopy of DNA-DAPI complexes. Microscopy Res. and Tech. 65(4-5), 205-217 (2004).
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| − | J-1 Inoue, M., M. A. Digman, M. Cheng, S. Y. Breusegem, N. Halaihel, V. Sorribas, W. W. Mantulin, E. Gratton, N. P. Barry and M. Levi.
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| − | Partitioning of NaPi cotransporter in cholesterol, sphingomyelin and glycosphingolipid enriched membrane domains modulates NaPi protein diffusion, clustering and activity. J Biol. Chem. 279 (47) 49160–49171 (2004).
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| − | J-2 Czeslik, C., G. Jackler, T. Hazlett, E. Gratton, R. Steitz, A. Wittemann and M. Ballauff. Salt-induced protein resistance of polyelectrolyte brushes studied using fluorescence correlation spectroscopy and neutron reflectometry. Phys . Chem. Chem.
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| − | Phys. 6, 5557–5563 (2004).
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| − | J-3 Janosch, S., C. Nicolini, B. Ludolf, C. Peters, M. Volkert, T.L. Hazlett, E. Gratton, H. Waldmann and R. Winter. Partitioning of dual-lipidated peptides into membrane microdomains - lipid sorting vs. peptide aggregation. J. Amer. Chem. Soc.
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| − | 126(24), 7496-7503 (2004).
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| − | J-4 Rao, S., J. Sutin, R. Clegg, E. Gratton, M. H. Nayfeh, S. Habbal, A. Tsolakidis and R. M. Martin. Excited states of tetrahedral single-core Si29 nanoparticles. Phys. Rev. B 69, 205319 (2004).
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| − | J-5 Safonova L.P., A. Michalos, U. Wolf, M. Wolf, D.M. Hueber, J.H. Choi, R. Gupta, C. Polzonetti, W.W. Mantulin and E. Gratton. Age-correlated changes in cerebral hemodynamics assessed by near-infrared spectroscopy. Archives of Gerontology
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| − | and Geriatrics 39(3), 207-225 (2004).
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| − | J-6 Ruan, Q., M. A. Cheng, M. Levi, E. Gratton and W. W. Mantulin. Spatial-temporal studies of membrane dynamics: scanning fluorescence correlation spectroscopy (SFCS). Biophys J 87, 12601267 (2004).
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| − | J-7 Czeslik, C., R. Jansen, M. Ballauff, A. Wittmann, C. A. Royer, E. Gratton and T. Hazlett. Mechanism of protein binding to spherical polyelectrolyte brushes studied in situ using two-photon excitation fluorescence fluctuation spectroscopy. Phys.
| |
| − | Rev. E 69, 021401-021409 (2004).
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| − | J-8 Morren, G., U. Wolf, P. Lemmerling, M. Wolf, J.H. Choi, E. Gratton, L. De Lathauwer and S. Van Huffel.
| |
| − | Detection of fast neuronal signals in the motor cortex from functional near infrared spectroscopy measurements using independent component analysis. Med. Biol. Eng. Comp. 42(1), 92-99 (2004).
| |
| − | J-9 Kis-Petekova, K. and E. Gratton. Distance Measurement by Circular Scanning of the Excitation Beam in the Two-Photon Microscope. Microsc Res Tech 63 (1), 34-49 (2004).
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| − | J-10 Choi, J.H., W. Wolf, V. Toronov, U. Wolf, C. Polzonetti, L.P. Safonova, A. Michalos, W.W. Mantulin and E. Gratton, Noninvasive determination of the optical properties of the adult brain: Near infrared spectroscopy approach J. Biomed. Optics,
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| − | 9(1) 221-229 (2004).
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| − | J-11 Tanner, K. and E. D’Amico, A. Kaczmarowski, S. Kukreti, J. Malpeli, W. W. Mantulin and E. Gratton. Spectrally resolved neurophotonics: A case report of hemodynamics and vascular components in the mammalian brain. J. of Biomed. Optics 10,
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| − | 064009-1-9 (2005).
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| − | J-12 Levi, V., Q. Ruan, M. Plutz, A. S. Belmont, and E. Gratton. Chromatin dynamics in interphase cells revealed by tracking in a two-photon excitation microscope. Biophys. J. 89, 4275–4285 (2005).
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| − | J-13 Gokhale, N. A., A. Abraham, M. A. Digman, E. Gratton, and W. Cho. Phosphoinositide specificity of and mechanism of lipid domain formation by annexin A2-p11 heterotetramer. J. Biol. Chem. 280(52), 42831-42840 (2005).
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| − | J-14 Eckhoff, D. A., J. D. B. Sutin, R. M. Clegg, E. Gratton, E. V. Rogozhina, P. V. Braun. Optical Characterization of Ultrasmall Si Nanoparticles Prepared through Electrochemical Dispersion of Bulk Si. J. Phys. Chem. B , 109(42), 19786-19797
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| − | (2005).
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| − | J-15 Digman, M. A., C. M. Brown, P. Sengupta, P. W. Wiseman, A. R. Horwitz and E. Gratton. Measuring Fast Dynamics in Solutions and Cells with a Laser Scanning Microscope. Biophys. J. 89, 1317-1327 (2005).
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| − | J-16 Digman, M. A., P. Sengupta, P. W. Wiseman, C. M. Brown, A. R. Horwitz, and E. Gratton. Fluctuation Correlation Spectroscopy with a Laser-Scanning Microscope: Exploiting the Hidden Time Structure. Biophys. J. Biophysical Letters: 88: L33-
| |
| − | 36L (2005).
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| − | J-17 Arnulphi, C., S. A. Sánchez, M. A.Tricerri, E. Gratton and A. Jonas. Interaction of Human Apolipoprotein A-I with Model Membranes Exhibiting Lipid Domains. Biophys. J. 89, 285-295 (2005).
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| − | J-18 Sanchez, S. A. and E. Gratton. Lipid-protein interactions revealed by two-photon microscopy and fluorescence correlation spectroscopy. Acc. Chemical Research 38, 469-477 (2005).
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| − | J-19 Levi, V., Q. Ruan, and E. Gratton. 3-D Particle Tracking in a Two-Photon Microscope: Application to the Study of Molecular Dynamics in Cells. Biophys. J. 88, 2919-2928 (2005).
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| − | J-20 Gratton, E., V. Y. Toronov, U. Wolf, M. Wolf, A. G. Webb. Measurement of brain activity by near-infrared light. J. Biomedical Optics 10(01), 1-13 (2005).
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| − | J-21 Tricerri M.A., J. D. Toledo, S. A. Sanchez, T. L. Hazlett, E. Gratton, A. Jonas and H. A. Garda. Visualization and analysis of apolipoprotein A-I interaction with binary phospholipid bilayers. J. Lipid Res. 46(4), 669-678 (2005).
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| − | J-22 Hanson, K., E. Gratton, and C. J. Bardeen. Sunscreen enhancement of UV-induced reactive oxygen species in the skin. Free Radic Biol Med 41(8):1205-12 (2006).
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| − | J-23 Nicolini, C., A. Celli, E. Gratton, and R. Winter. Pressure tuning of the morphology of heterogeneous lipid vesicles: a two-photon-excitation fluorescence microscopy study. Biophys J 91(8):2936-42 (2006).
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| − | J-24 Eckhoff, D.A., J. N. Stuart, J. D. B. Sutin, J. V. Sweedler, and E. Gratton. Capillary electrophoresis of ultrasmall carboxylate functionalized silicon nanoparticles. J Chem Phys 125(8):081103 (2006).
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| − | J-25 Rogozhina, E. V., D. A. Eckhoff, E. Gratton and P. V. Braun. Carboxyl functionalization of ultrasmall luminescent silicon nanoparticles through thermal hydrosilylation. J. Materials Chemistry 16, 1421-1430 (2006).
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| − | J-26 Nicolini, C., J. Baranski, S. Schlummer, J. Palomo, M. Lumbierres-Burgues, M. Kahms, J. Kuhlmann, S. Sanchez, E. Gratton, H. Waldmann and R. Winter.
| |
| − | Visualizing association of N-Ras in lipid microdomains: Influence of domain structure and interfacial adsorption. JACS, 192-201 (2006).
| |
| − | J-27 Simonson, P., E. D’Amico and E. Gratton. Modulation of an optical needle’s reflectivity alters the average photon path through scattering media. J. Biomedical Optics, 11(1) 014023-1-9 (2006).
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| − | J-28 Ragan, T., H. Huang, P. So and E. Gratton. 3D particle tracking on a two-photon microscope. J. Fluorescence (2006).
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| − | J-29 Levi, V., V. I. Gelfand, A. S. Serpinskaya and E. Gratton. Melanosomes Transported by Myosin V in Xenopus Melanophores Perform Slow 35 nm Steps. Biophys. J. (2006).
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| − | J-30 Levi, V., A. S Serpinskaya, E. Gratton, and V. Gelfand. Organelle transport along microtubules in Xenopus melanophores: evidence for cooperation between multiple motors. Biophys. J. 90, 318-327 (2006).
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| − | J-31 V R Caiolfa, M Zamai, G Malengo, A Andolfo, C D Madsen, J D B Sutin, M A Digman, E Gratton, F Blasi, and N Sidenius. Monomer–dimer dynamics and distribution of GPI-anchored uPAR are determined by cell surface protein assemblies. J
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| − | Cell Biol 2007; 179(5): 1067-1082.
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| − | J-32 C O Olopade, E Mensah, R Gupta, D Huo, D L Picchiett, E Gratton, and A Michalos. Noninvasive determination of brain tissue oxygenation during sleep in obstructive sleep apnea: a near-infrared spectroscopic approach. Sleep 2007; 30(12):
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| − | 1747-1755.
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| − | J-33 U Wolf, M Wolf, J-H Choi, L A Paunescu, A Michalos, and E Gratton. Regional differences of hemodynamics and oxygenation in the human calf muscle detected with near-infrared spectrophotometry. J Vasc Interv Radiol 2007; 18(9): 1094-
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| − | 1101.
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| − | J-34 R Gatto, W Hoffman, C Paisansathan, W W Mantulin, E Gratton, and F T Charbel. Effect of age on brain oxygenation regulation during changes in position. J Neurosci Methods 2007; 164(2): 308-311.
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| − | J-35 S A Sánchez, M A Tricerri, and E Gratton. Interaction of high density lipoprotein particles with membranes containing cholesterol. J Lipid Res 2007; 48(8): 1689-1700.
| |
| − | J-36 V Levi and E Gratton. Exploring dynamics in living cells by tracking single particles. Cell Biochem Biophys 2007; 48(1): 1-15.
| |
| − | J-37 S Kukreti, A Cerussi, B Tromberg, and E Gratton. Intrinsic tumor biomarkers revealed by novel double-differential spectroscopic analysis of near-infrared spectra. J Biomed Opt 2007; 12(2): 020509.
| |
| − | J-38 N Boens, W Qin, N Basari, J Hofkens, M Ameloot, J Pouget, J-P Lefèvre, B Valeur, E Gratton, M vandeVen, N D Silva, Jr, Y Engelborghs, K Willaert, A Sillen, G Rumbles, D Phillips, A J W G Visser, A van Hoek, J R Lakowicz, H Malak, I
| |
| − | Gryczynski, A G Szabo, D T Krajcarski, N Tamai, and A Miura. Fluorescence lifetime standards for time and frequency domain fluorescence spectroscopy. Anal Chem 2007; 79(5): 2137-49.
| |
| − | J-39 M Calderon-Arnulphi, A Alaraj, S Amin-Hanjani, W W Mantulin, C M Polzonetti, E Gratton, and F T Charbel. Detection of cerebral ischemia in neurovascular surgery using quantitative frequency-domain near-infrared spectroscopy. J Neurosurg
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| − | 2007; 106(2): 283-290.
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| − | J-40 K Tanner, E Beitel, E D'Amico, W W Mantulin, and E Gratton. Effects of vasodilation on intrinsic optical signals in the mammalian brain: a phantom study. J Biomed Opt 2007; 11(6): 064020.
| |
| − | J-41 O Barreiro, M Zamai, M Yanez-Mo, E Tejera, P Lopez-Romero, P N Monk, E Gratton, V R Caiolfa, and F Sanchez-Madrid. Endothelial adhesion receptors are recruited to adherent leukocytes by inclusion in preformed tetraspanin nanoplatforms.
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| − | J Cell Biol. 2008; 183(3): 527-542. PMCID: PMC2575792
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| − | J-42 G Malengo, A Andolfo, N Sidenius, E Gratton, M Zamai, and V R Caiolfa.
| |
| − | Fluorescence correlation spectroscopy and photon counting histogram on membrane proteins: functional dynamics of the glycosylphosphatidylinositol-anchored urokinase plasminogen activator receptor. J Biomed Opt 2008; 13(3): 031215.
| |
| − | J-43 V Levi and E Gratton. Chromatin dynamics during interphase explored by single-particle tracking. Chromosome Res 2008; 16(3): 439-449.
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| − | J-44 S Kwok, C Y Lee, S A Sánchez, T L Hazlett, E Gratton, and Y Hayashi. Genetically encoded probe for fluorescence lifetime imaging of CaMKII activity. Biochem Biophys Res Commun 2008; 369(2): 519-525. PMCID: PMC2396457
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| − | J-45 M A Digman, C M Brown, A R Horwitz, W W Mantulin, and E Gratton. Paxillin dynamics measured during adhesion assembly and disassembly by correlation spectroscopy. Biophys J 2008; 94(7): 2819-2831.
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| − | J-46 A Garcia-Marcos, S A Sánchez, P Parada, J S Eid, D M Jameson, M Remacha, E Gratton, and J P G Ballesta. Yeast ribosomal stalk heterogeneity in vivo shown by two-photon FCS and molecular brightness analysis.
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| − | Biophys J 2008; 94(7): 2884-2890.
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| − | J-47 M A Digman, R Dalal, A R Horwitz, and E Gratton. Mapping the number of molecules and brightness in the laser scanning microscope. Biophys J 2008; 94(6): 2320-2332.
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| − | J-48 C B Raub, J R Unruh, V Suresh, T Krasieva, T Lindmo, E Gratton, B J Tromberg, and S C George. Image correlation spectroscopy of multiphoton images correlates with collagen mechanical properties. Biophys J 2008; 94(6): 2361-2373.
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| − | J-49 R A Colyer, C Y Lee, and E Gratton. A novel fluorescence lifetime imaging system that optimizes photon efficiency. Microsc Res Tech 2008; 71(3): 201-213.
| |
| − | J-50 S A Sánchez, M A Tricerri, and E Gratton. Detecting cholesterol changes in lipid bilayers. BioWorld Europe 2008; 1: 8-11.
| |
| − | J-51 M A Digman, V R Caiolfa, M Zamai, and E Gratton. The Phasor approach to fluorescence lifetime imaging analysis. Biophys J 2008; 94(2): L14-16.
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| − | J-52 R Fiorini, L Ragni, S Ambrosi, G P Littarru, E Gratton, and T Hazlett. Fluorescence studies of the interactions of ubiquinol-10 with liposomes. Photochem Photobiol 2008; 84(1): 209-214.
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| − | J-53 R B Dalal, M A Digman, A R Horwitz, V Vetri, and E Gratton. Determination of particle number and brightness using a laser scanning confocal microscope operating in the analog mode. Microsc Res Tech 2008; 71(1): 69-81.
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| − | J-54 A Celli, S Beretta, and E Gratton. Phase fluctuation on the micron-submicron scale in GUVs composed of a binary lipid mixture. Biophys J 2008; 94(1): 104-116.
| |
| − | J-55 C M Brown, R B Dalal, B Hebert, M A Digman, A R Horwitz, and E Gratton. Raster image correlation spectroscopy (RICS) for measuring fast protein dynamics and concentrations with a commercial laser scanning confocal microscope. J Microsc
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| − | 2008; 229(1): 78-91.
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| − | J-56 H Sanabria, M A Digman, E Gratton, and M N Waxham. Spatial Diffusivity and availability of intracellular Calmodulin. Biophys J 2008; 95(12): 6002-6015. PMCID: PMC2599858
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| − | J-57 J R Unruh and E Gratton. Analysis of molecular concentration and brightness from fluorescence fluctuation data with an electron multiplied CCD camera. Biophys J 2008; 95(11): 5385-5398. PMCID: PMC2586556
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| − | J-58 C Hellriegel and E Gratton. Real-time multi-parameter spectroscopy and localization in three-dimensional single-particle tracking. Theodor Forster Lecture Series on Quantitative Fluorescence Microscopy, University of Cambridge, UK 2007. J R
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| − | Soc Interface. 2009; 6 (Suppl 1):S3-S14. PMCID: PMC2706464
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| − | J-59 M A Digman, P W Wiseman, A R Horwitz, and E Gratton. Detecting protein complexes in living cells from laser scanning confocal image sequences by the cross correlation raster image spectroscopy method. Biophys J 2009; 96(2): 707-716.
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| − | PMCID:PMC2716688
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| − | J-60 M A Digman, E Gratton. Analysis of diffusion and binding in cells using the RICS approach. Microsc Res Tech. 2009; 72(4): 323-332.
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| − | J-61 S Kukreti, A Cerussi, B Tromberg, and E Gratton. Intrinsic near-infrared spectroscopic markers of breast tumors. Disease Markers (IOS Press), 2008; 25(6): 281-290. PMCID: PMC2732199
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| − | J-62 M Digman and E Gratton. Fluorescence Correlation Spectroscopy and Fluorescence Cross-Correlation Spectroscopy. Wiley Interdisciplinary Reviews: Systems Biology and Medicine 2009; 1(2): 273-282.
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| − | J-63 M A Digman, P W Wiseman, C K Choi, A R Horwitz, and E Gratton. Stoichiometry of molecular complexes at adhesions in living cells. Proc Natl Acad Sci USA. 2009; 106(7): 2170-2175. PMCID: PMC2630200
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| − | J-64 K Tanner, D R Ferris, L Lanzano, B Mandefro, W W Mantulin, D M Gardiner, E Rugg, and E Gratton. Coherent movement of cell layers during wound healing by image correlation spectroscopy. Biophys J. 2009; 97(7) : 20-98-2106. PMCID:
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| − | PMC2756390
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| − | J-65 Ellen Gielen, Nick Smisdom, Martin J vandeVen, Ben De Clercq, Enrico Gratton, Michelle A Digman, Jean-Michel Rigo, Johan Hofkens, Yves Engelborghs, and Marcel Ameloot.
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| − | Measuring diffusion of lipid-like probes in artificial and natural membranes by raster image correlation spectroscopy (RICS): Use of a commercial laser-scanning microscope with analog detection. Langmuir. 2009; 25(9): 5209-5218.
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| − | PMCID: PMC2728053
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| − | J-66 C A Toro, S A Sanchez, A Zanocco, E Lemp, E Gratton, and G Gunther. Solubilization of lipid bilayers by myristyl sucrose ester: effect of cholesterol and phospholipid head group size. Chem. Phys Lipids. 2009; 157(2): 104-112.
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| − | J-67 E Gratton and M Digman. One photon up, one photon down. Nat Biotechnol. 2009; 27(2): 147-148.
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| − | J-68 M J Rossow, W W Mantulin, and E Gratton. Spatiotemporal image correlation spectroscopy measurements of flow demonstrated in micrfluidic channels. J Biomed Opt. 2009; 14(2): 024014. PMCID: PMC2702990.
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| − | J-69 G Caracciolo, M Digman, E Gratton, S A Sanchez, and R Caminiti. Efficient escape from endosomes determines the superior efficiency of multicomponent lipoplexes. J phys Chem B. 2009; 113(15): 4995-4997. PMCID: PMC2673460.
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| − | J-70 K Krishnan, o Holub, E Gratton, A H A Clayton, S cody, and P D J Moens. Profilin interaction with phosphatidylinositol (4,5)-bisphosphate destabilizes the membrane of giant unilamellar vesicles. Biophys J. 2009; 96(12): 5112-5121. PMCID:
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| − | PMC2712054
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| − | J-71 M A Digman and E Gratton. Imaging barriers to diffusion by pair correlation functions. Biophys J.2009; 97(2): 665-673. PMCID: PMC2711318
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| − | J-72 Y Katayama, O Burkacky, M Myer, C Brauchle, E Gratton, and D C Lamb. Real-time nanomicroscopy via three-dimensional single particle tracking. ChemPhysChem. 2009; 10(14): 2458-2464.
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| − | J-73 A Celli and E Gratton. Dynamics of lipid domain formation: fluctuation analysis. Biochim Biophys Acta. 2009; [epub ahead of print].
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| − | J-74 E Gratton, V Toronov, U Wolf and M Wolf. Detection of brain activity by near-infrared light. Biomedical Optical Imaging. By JG Fujimoto and D Farkas (Editors). Oxford University Press, pp. 378-395, 2009. ISBN: 9780195150445
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| − | J-75 M Digman and E Gratton. Multicolor fluctuation spectroscopy in cells. BiOS 2009. Part of SPIE Photonics West. San Jose, California, January 24-29, 2009. Multiphoton Microscopy in the Biomedical Sciences IX (Proceedings of SPIE, Vol. 7183).
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| − | By A periasamy and PTC So (Editors). 718303, 2009. ISBN: 978081947429
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| − | J-76 S Kukreti, A E Cerussi, W Tanamai, D Hsiang, B J Tromberg, and E Gratton. Characterization of metabolic differences between benign and malignant tumors: high-spectral-resolution diffuse optical spectroscopy. Radiology .2010; 254(1): 277-284.
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| − | PMCID: PMC2797652
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| − | J-77 Y Yoon, J Tong, P J Lee, A Albanese, N Bhardawaj, M Kallberg, M A Digman, H Lu, E Gratton, Y-K Shin, and W Cho. Molecular basis of the potent membrane remodeling activity of the epsin1 ENTH domain. J Biol Chem. 2010; 285(1): 531-
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| − | 540. PMCID: PMC2804201
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| − | J-78 A Celli, S A Sanchez, M J Behne, T L Hazlett, E Gratton, and T M Mauro. The epidermal Ca(2+) gradient: measurement using the phasor representation of fluorescent lifetime imaging. Biophys J. 2010; 98(5): 911-921. PMCID: PMC2830439.
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| − | J-79 S A Sanchez, M A Tricerri, G Ossato, and E Gratton. Lipid packing determines protein-membrane interactions: Challenges for apoliprotein A-I and High Density Lipoproteins. Biochim Biophys Acta. 2010; [epub ahead of print].
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| − | J-80 F Cardarelli and E Gratton. In vivo imaging of single-molecule translocation through nuclear pore complexes by pair correlation functions. PLoS ONE. 2010; 5(5): e10475.
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| − | J-81 M Rossow, W Mantulin and E Gratton. Scanning laser image correlation for measurement of flow. J Biomed Opt. 2010; 15(2): 026003
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| − | J-82 G Ossato, M Digman, C Aiken, T Lukacsovich, J Marsh, and E Gratton. A two-step path to inclusion formation of huntingtin peptides revealed by number and brightness analysis. Biophys J. 2010: 98(12): 3078-3085
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| − | J-83 E Hinde, F Cardarelli, M Digman, and E Gratton.In vivo pair correlation analysis of EGFP intranuclear diffusion reveals DNA-dependant molecular flow. Proc Natl Acad Sci USA. 2010; 107(38): 16560-16565
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| − | J-84 K Azertash, C Nein Shy, K Flynn, J Jester, and E Gratton. Non-invasive in vivo measurement of the tear film using spatial autocorrelation in a live mammal model.Biomed Opt Express. 2010; 1(4): 1127-1137
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| − | J-85 M Rossow, J Sasaki, M Digman, and E Gratton. Raster Image Correlation spectroscopy in live cells. Nat Protoc. 2010; 5(11): 1761-1774
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| − | J-86 C Fu, G Ossato, M Long, M Digman, A Gopinathan, L Lee, E Gratton and M Khine. Bimetallic nanopetals for thousand-fold dluoresence enhancements. Appl Phys let. 2010; 97(20): 203101
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| − | J-87 S Kim, H Sanabria, M Digman, E Gratton, P Schwille, W Zipfel, and M N Waxham. Quantifying translational mobility in neurons: comparison between current optical techniques. J Neurosci. 2010; 30(49): 16409-16416
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| − | J-88 M Behne, S Sanchez, N Barry, N Kirschner, W Meyer, T Mauro, I Moll and E Gratton. Major translocation of calcium upon epidermal barrier insult: imaging and quantification via FLIM/Fourier vector analysis. Arch Dermatol Res. 2010; [Epub
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| − | ahead of print]
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| − | J-89 M Digman and E Gratton Lessons in Fluctuation Correlation Spectroscopy. Ann Rev Phys Chem. 2011; [Epub ahead of print]
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Enrico Gratton received his doctorate in physics in 1969 from the University of Rome. In 1986, while a Professor at the University of Illinois at Urbana-Champaign, Dr. Gratton was awarded a grant from the National Institutes of Health to establish the first national facility dedicated to fluorescence spectroscopy: the Laboratory for Fluorescence Dynamics (LFD). The LFD is a state-of-the-art fluorescence laboratory for use by local, national, and international scientists. It is committed to service in a user-oriented facility, as well as to research and development of fluorescence instrumentation and theory. The LFD has reached international recognition for the development of instrumentation for time-resolved fluorescence spectroscopy using frequency domain methods. In 2006 the entire LFD laboratory moved to its current location at the new Natural Sciences II building at the University of California, Irvine. Dr. Gratton remains Principal Investigator of the LFD and holds joint appointments as Professor in the UCI departments of Biomedical Engineering and Physics, and also in the College of Medicine. Dr. Gratton collaborates with other UCI researchers in the areas of engineering, medicine, physical science, information and computer science, biological science, and UCI's Beckman Laser Institute (BLI).
Dr. Gratton and his engineering group are involved in a collaboration with Bruce Tromberg and his colleagues at BLI which employs noninvasive, safe near-infrared optical technology in the study of breast cancer and the effectiveness of chemotherapy in younger women. The scanner they have developed is currently in Phase 2 clinical trials and works by measuring molecular and functional changes in the breast that are indicators of cancer. Additionally, Dr. Gratton's lab has developed a novel procedure for the analysis of the spectroscopic signature in breast cancer. This study has lead to the discovery of specific spectroscopic markers for breast tumors. These markers appear to be different for benign and malignant tumors, opening new perspective for effective optical biopsy.
In the areas of biology and biophysics, Dr. Gratton utilizes his knowledge of the latest techniques in fluorescence spectroscopy and microscopy to image live cells. As head of the Laboratory for Fluorescence Dynamics, a National Center for Research Resources supported by the National Institutes of Health, he and the scientists in his lab use fluorescence to study cellular processes including protein aggregation, membrane interactions, and migration of cells, to track moving particles, and to analyze collagen formation and deformation. The research leads to a better understanding of cell function, with potential application to diagnosing and identifying treatment for many human diseases, including Huntington's disease, kidney disorders, and cancers. Their findings also lead to the development of new fluorescence instrumentation and to the continued advancement of his center's data analysis software, Globals for Spectroscopy and Globals for Imaging. Proceeds from the software are used to fund research-related conferences and workshops, reflecting the longstanding commitment of Dr. Gratton and his lab to disseminating the latest advances in biomedical research to the greater scientific community.
