Sackmann Erich

Erich Sackmann

Erich Sackmann did the Diploma (1961) and the Ph.D. in Physics (1964) at the University Stuttgart (with Theodor Förster) and his Habilitation at the University of Göttingen (1973). He was a Member of Technical Staff at Bell Telephone Laboratories and research assistant at the Max Planck Institute for Biophysical Chemistry, Göttingen. From 1974 until his retirement in 2003 he served as Professor of Physics and Director of the Biophysics Institutes at the University of Ulm and the Technical University Munich (since 1980).

He served guest professor at the University of British Columbia (Vancouver), at the Stanford University, at the Institute Curie in Paris. He spent a term as Regents Professor at the University of California at Los Angeles (UCLA) and guest professor at the ETH Lausanne.

Research Interests

1960-1968: NMR-spectroscopy of organic molecules-Physics of liquid crystals-Photophysik of organic solids. 1970-2003: Physics of biological and biomimetic materials (cell membranes, actin based cytoskeleton, biomimetics of tissue and cell surfaces, biosensors, the physical basis of cell adhesion). Since 2000: Physics of the cell (cell locomotion, micro-viscoelasticity of cells, logistic self-assembly of membrane based functional machines).

Administrational Activites

From 1974–1980: President of the German Biophysical Society and founding member of the Biological Physics Section in the German Physical Society.

From 1989-1991: Dean of the Faculty of Physics of the Technical University Munich.

From 1988-2000: chairman of the Munich Interdisciplinary Research Project ”: Biological and Artificial Interfaces on Solids".

Awards

2001 Oswald Award of the German Colloid Society

2002: Fellow of the American Physical Society

2006 Stern-Gerlach Medal of the Deutsche Physikalische Gesellschaft

Selected Papers

NMR Spectrocopy

Dreeskamp Herbert and Erich Sackmann.1962.Bestimmung des Vorzeichens der Spin-Spin-Kopplungskonstanten zwischen Protonen und C13. Z. Phys. Chem. N.F. 34, 262-266

Liquid Crystals

Sackmann, Erich, Saul Meiboom and Laurent Snyder.1968. The Nuclear Magnetic Resonance Spectra of Enantiomers in Optically Active Liquid Crystals. J. Amer. Chem. Soc. 90, 2183-2386.

Sackmann, Erich.1968.On the Polarization of Optical Transitions of Dye Molecules Oriented in an Ordered Glass Matrix. J. Amer. Chem. Soc. 90, 3569-3571.

Sackmann, Erich. 1971.Photochemically Induced Reversible Color Changes in Cholesteric Liquid Crystals. J. Amer. Chem. Soc. 93, 7088-7092.

Phophysics of aromatic molecular crystals

Möhwald Helmut and Erich Sackmann.1974. Localized Excited Triplet States in Mixed Charge-transfer; Single Crystals: Formation of Excited Multicomplexes. Chem. Phys. Lett. 26, 509-513

Physics of biological membranes

TräubleHermann and Erich Sackmann. 1972. Studies of the Crystalline-Liquid Crystalline Phase Transitions of Lipid Model Membranes.J. Amer. Chem. Soc. (1972) 94, 4499-4508.

Träuble Hermann and Erich .1975 Lipid Motion and Rhodopsin Rotation.Nature 245, 210-2013.

Gebhardt Christian, Hans Gruler and Erich Sackmann. 1977, On Domain Structure and Local Curvature in Lipid Bilayers and Biological Membranes. Z. Naturf. 32c, 582-596.

Albrecht, Otto, HansGruler, and Erich Sackmann. 1978.Polymorphism of Phospholipid Monolayers.Journal de Physique 39, 301-321.

J. Engelhardt, H. Gaub and E. SackmannViscoelastic Properties of Erythrocyte Membranes in high Frequency Electric Fields.Nature (1984) 307, 378-380.

Fischer Albrecht and Erich Sackmann.1985. A charge-decoration technique for studying the heterogeneity of coexisting monolayer phases by electron microscopy. Nature 313, 299-302.

Evans, Evan, and Erich Sackmann.1988.Translational and rotational drag coefficients for a disk moving in a liquid membrane associated with a rigid substrate.J. Fluid Mechanic194, 553-561.

Physics of the Actin Cytoskeleton.

Müller Otto, Hermann Gaub, Michael Bärmannand Erich Sackmann.1991.Viscoelasti moduli of sterically and chemically cross-linked actin networks in dilute and semi-diluteregime: measurements by an oscillating disc rheometer.Macromolecules 24, 3111-3120.

Ziemann, Florian, Joachim Rädler and Erich Sackmann. 1994. Local Measurements of Viscoelastic Moduli of Entagled Actin Networks Using an Oscillating Magnetic Bead Micro-Rheometer. Biophys.J. 66, 2210-2216.

Dichtl Markus and Erich Sackmann.1999. Colloidal Probe Study of Short Time Local and Long Time Reptational Motions of Semiflexible Macromolecules in Entangled Networks New. J. Phys. 1, 18.1-18.4.

Limozin Laurant and Erich Sackmann.2002 Polymorphism of Cross-Linked Actin Networks in Giant Vesicles, Phys. Rev. Lett.16, 8103- 8104.

Membrane Elasticity and cell shape changes

Sackmann Erich, Hans-Peter Duwe and Hans Engelhardt .1986.Membrane bending elasticity and its role for shape fluctuations and shape transformations of cells and vesicles.Faraday Discuss, Chem. Soc. 81, 281-290.

Berndl, Kurt, Joseph Käs. Reinhardt. Lipowsky, Udo Seifert and Erich Sackmann.1990.Shape Transformations of Giant Vesicles: Extreme Sensitivity to Bilayer Asymmetry. Europhys.13, 659-664

Käs, Josef. Helmut. Strey and Erich Sackmann. 1994. Direct imaging of reptation of semiflexible actin filaments. Nature 368, 226-229.

KäsJosef and Erich Sackman.1991. Shape transitions and shape stability of giant phospholipid vesicles in pure water induced by area-to-volume changes.Biophys. J. 60, 825-844

Zilker, Andreas, Markus Ziegler and Erich Sackmann. 1992. Spectral analysis of erythrocyte flickering in the 0.3-4-µm-1 regime by microinterferometry combined with fast image processing. Phys. Rev. A. 46, 7998-8001.

Tempel, Markus Gerhardt Isenberg and Erich Sackmann. 1996. Temperature-induced sol-gel transition and microgel formation in alpha-actinin cross-linked actin networks: A rheological study. Phys. Rev. E 54, 1802-1810.

Hinner, Berhar Markus Tempel, Erich Sackmann, Klaus Kroyand Erwin. Frey 1998. Entanglement, Elasticity, and Viscous Relaxation of Actin Solutions. Phys. Rev. Lett. 81, 2614-2617.

Physics of Cell Adhesion Rädler, Joachim,ToniFeder,Helmut Streyand Erich Sackmann. 1995.Fluctuation analysis of tension-controlled undulation forces between giant vesicles and solid substrates.Phys. Rev. E. 51, 4526-4536

E. Sackmann Erich Supported Membranes. 1996. Scientific and Practical Applications.Science.271, 43-48.

J. Nardi, Johann RobijnBruinsma and Erich Sackmann-1998.Adhesion-Induced Reorganization of Charged Fluid Membranes.Phys. Rev. E (1998) 58, 6340-6354.

Nardi, Johann, Robijn Bruijnsma and Erich Sackmann. 1999. Vesicles as Osmotic Motors Phys. Rev. Lett82, 5168-5171 Biosensors based on solid supported membranes

Wiegand, Gerald. Neumaier.Kurtand Erich Sackmann. 2000. Fast Impedance Spectroscopy :General Aspects and Performance Study for Single Ion Channel Measurements- Rev Sci.Instruments 71, 2309-2320

Bruinsma, Robijn, AlmuthBehrisch and Erich Sackmann. 2000. Adhesive Switching of Membranes: Experiment and Theory. Phys. Rev. E 61, 4253-4267.

Guttenberg,Zeno B. Lorz, Barbara E. Sackmann Etichand Alexis Boulbitch, 2001. First-Order Transition between Adhesion States in a System of Mimicking Cell-Tissue Interaction Europhys.Lett.54, 826-832.

Physics of the cell

Feneberg, Wolfgang,MartinAepfelbacher, and Erich Sackmann. 2004. Micro-Viscoelasticity of the Apical Cell Surface of Human Umbilical Endothelial Cells (HUVEC) within Confluent MonolayersBiophys. J 87 1-12.

Tanaka Motomu and Erich Sackmann. 2005, Polymer supported membrane as models of the cell surface. Nature 437, 656-660

Zidovska Alexandra and Erich Sackmann,2006.Phys. Brownian Motion of Nucleated Cell Envelopes Impedes Adhesion. Phys. Rev. Lett. 96, 048103

Arzinet, Bernd Meier, Erich Sackmann, Joachim O. Rädler, andDoris Heinrich.Temporal Analysis ofActive and Passive Transport in Living Cells (2008) Phys. Rev. Lett. 101, 248103.

Sackmann, Erich.2014.Endoplasmatic reticulum shaping by generic mechanisms and protein-induced spontaneous curvature Adv. Colloid .Interface Sci. 208, 153–160.

Sackmann Erich, and Smith, Ana. 2014, Physics of cell adhesion: some lessons from celbiomimetic systems. Soft Matter, 10, 1644-1649

Sackmann, Erich. 2011. Quantal law of immune response New J. Physics 13, 065013.

Sackmann, Erich, Felix Keber and Doris Heinrich. 2010. Physics of Cellular Movements. Annu.Rev. Condens. Matter Phys. 1:257–76

Sackmann Erich. 2015. How actin/myosin crosstalks guide the adhesion, locomotion and polarization of cells. Biochim.Biophys.Acta 1853, 3132–3142.

G. Meier, E. Sackmann, J.C. Grabmaier: Applications of Liquid Crystals (Springer Verlag Berlin Heidelberg New York, 1975)

Lipowsky R. and Erich Sackmann (eds): Structure and Dynamics of Membranes. Handbook of Biological Physics vol. 1A, 1B (North Holland Amsterdam, 1995).

E. Sackmann Erich and Rudolf . Merkel Lehrbuch der Biophysik.Wiley Verlag Berlin 2009.